scholarly journals Author Correction: NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lukas Grätz ◽  
Katharina Tropmann ◽  
Merlin Bresinsky ◽  
Christoph Müller ◽  
Günther Bernhardt ◽  
...  
Keyword(s):  
Binding Assay ◽  
Receptor Ligands ◽  
Histamine H2 Receptor ◽  
H2 Receptor

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

scholarly journals Author Correction: NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Lukas Grätz ◽  
Katharina Tropmann ◽  
Merlin Bresinsky ◽  
Christoph Müller ◽  
Günther Bernhardt ◽  
...  
Keyword(s):  
Binding Assay ◽  
Receptor Ligands ◽  
Histamine H2 Receptor ◽  
H2 Receptor

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

scholarly journals NanoBRET binding assay for histamine H2 receptor ligands using live recombinant HEK293T cells

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Lukas Grätz ◽  
Katharina Tropmann ◽  
Merlin Bresinsky ◽  
Christoph Müller ◽  
Günther Bernhardt ◽  
...  
Keyword(s):  
Binding Assay ◽  
Receptor Ligands ◽  
Histamine H2 Receptor ◽  
H2 Receptor

Structure-Activity Relationships of Histamine H2 Receptor Ligands+

2004 ◽  
Vol 4 (9) ◽  
pp. 941-954 ◽  
Author(s):  
Stefan Dove ◽  
Sigurd Elz ◽  
Roland Seifert ◽  
Armin Buschauer
Keyword(s):  
Receptor Ligands ◽  
Histamine H2 Receptor ◽  
H2 Receptor ◽  
Structure Activity Relationships ◽  
Structure Activity

scholarly journals VIRTUAL TARGET CONSTRUCTION FOR STRUCTURE-BASED SCREENING IN THE DISCOVERY OF HISTAMINE H2 RECEPTOR LIGANDS

2021 ◽  
pp. 239-241
Author(s):  
GERRY NUGRAHA ◽  
ENADE PERDANA ISTYASTONO
Keyword(s):  
Molecular Dynamics ◽  
Md Simulations ◽  
Receptor Ligands ◽  
Reference Compound ◽  
Histamine H2 Receptor ◽  
H2 Receptor ◽  
Docking Simulations ◽  
Virtual Target ◽  
Free Energy Of Binding ◽  
Human Histamine

Objective: This study aimed to develop validated targets to be employed in structure-based virtual screening (SBVS) to discover ligands for the human histamine H2 receptor (hHRH2). Methods: The virtual targets construction was initiated by homology modeling with the reference compound ranitidine as the ligand followed by 100 ns molecular dynamics (MD) simulations. During MD simulations, the snapshot with the lowest value of the free energy of binding was selected for further validation by re-docking simulations. All simulations were performed in YASARA-Structure. Results: The research presented here resulted in one validated target for the SBVS. Additionally, by employing a clustering module in MD simulations analysis in YASARA-Structure, more than ten different virtual targets are also available for further uses. Conclusion: The virtual targets resulted in this research offer possibilities to construct valid SBVS protocols to identify ligands for the hHRH2.

Synthesis and pharmacological characterization of novel fluorescent histamine H2-receptor ligands derived from aminopotentidine

2006 ◽  
Vol 16 (15) ◽  
pp. 3886-3890 ◽  
Author(s):  
Sheng-Xue Xie ◽  
Georgiana Petrache ◽  
Erich Schneider ◽  
Qi-Zhuang Ye ◽  
Günther Bernhardt ◽  
...  
Keyword(s):  
Receptor Ligands ◽  
Pharmacological Characterization ◽  
Histamine H2 Receptor ◽  
H2 Receptor

Dimeric carbamoylguanidine-type histamine H2 receptor ligands: A new class of potent and selective agonists

2015 ◽  
Vol 23 (14) ◽  
pp. 3957-3969 ◽  
Author(s):  
Nicole Kagermeier ◽  
Kristin Werner ◽  
Max Keller ◽  
Paul Baumeister ◽  
Günther Bernhardt ◽  
...  
Keyword(s):  
Receptor Ligands ◽  
Histamine H2 Receptor ◽  
H2 Receptor ◽  
New Class ◽  
Selective Agonists
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