Vascular patterns in reactive lymphoid tissue and in non-Hodgkin's lymphoma

The most common extranodal site for non-Hodgkin's lymphoma in the head and neck is the lymphoid tissue of Waldeyer's ring. Diffuse histiocytic non-Hodgkin's lymphoma is the most frequent type occurring at all head and neck extranodal sites. The rarity of histiocytic lymphoma in the areas comprising Waldeyer's ring tends to make assembly of a large series of patients for retrospective study quite difficult. Of the 804 patients treated for malignancies in Waldeyer's ring during the years 1948 to 1985 at the Charity Hospital of Louisiana, 26 had lesions classified as histiocytic non-Hodgkin's lymphoma. We present, to our knowledge, the largest series of diffuse histiocytic lymphomas involving Waldeyer's ring.

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Aggressive non-Hodgkin's lymphoma after successful eradication of Helicobacter pylori and regression of gastric lymphoma of mucosa-associated lymphoid tissue

Journal of Gastroenterology ◽

10.1007/s005350050162 ◽

1998 ◽

Vol 33 (5) ◽

pp. 724-727 ◽

Cited By ~ 1

Author(s):

Shinji Ohashi ◽

Kose Segawa ◽

Shozo Okamura ◽

Masahiro Mitake ◽

Humihiro Urano ◽

...

Keyword(s):

Helicobacter Pylori ◽

Lymphoid Tissue ◽

Hodgkin’S Lymphoma ◽

Gastric Lymphoma ◽

Hodgkin's Lymphoma ◽

Non Hodgkin’S Lymphoma ◽

Non Hodgkin's Lymphoma

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Expression of PIK3CA and FOXP1 in gastric and intestinal non-Hodgkin’s lymphoma of mucosa-associated lymphoid tissue type

Tumor Biology ◽

10.1007/s13277-011-0192-3 ◽

2011 ◽

Vol 32 (5) ◽

pp. 913-920 ◽

Cited By ~ 5

Author(s):

Linzhu Zhai ◽

Yuanyuan Zhao ◽

Sheng Ye ◽

He Huang ◽

Ying Tian ◽

...

Keyword(s):

Lymphoid Tissue ◽

Hodgkin’S Lymphoma ◽

Hodgkin's Lymphoma ◽

Tissue Type ◽

Non Hodgkin’S Lymphoma ◽

Non Hodgkin's Lymphoma

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Patterns of disease in localized extranodal lymphomas.

Journal of Clinical Oncology ◽

10.1200/jco.1987.5.6.875 ◽

1987 ◽

Vol 5 (6) ◽

pp. 875-880 ◽

Cited By ~ 59

Author(s):

M K Gospodarowicz ◽

S B Sutcliffe ◽

T C Brown ◽

T Chua ◽

R S Bush

Keyword(s):

Lymphoid Tissue ◽

Hodgkin’S Lymphoma ◽

Hodgkin's Lymphoma ◽

Lymphocyte Migration ◽

Migration Patterns ◽

Waldeyer’S Ring ◽

Distant Relapse ◽

Non Hodgkin’S Lymphoma ◽

Non Hodgkin's Lymphoma ◽

Independent Determinant

The site of origin of lymphoid tissue is an important determinant of lymphocyte migration patterns. The association of gastrointestinal (GI) and Waldeyer's ring lymphoma and the unique lymphocyte migration pattern of gut-associated lymphoid tissue (GALT) have been previously described. To establish whether predictive clinical patterns of disease occur in localized Non-Hodgkin's lymphoma, survival and relapse patterns for 496 patients with stage I and II non-Hodgkin's lymphoma (NHL) treated with loco-regional irradiation (XRT) alone were examined. We identified 139 patients with GALT lymphoma (defined as arising from primitive gut and including Waldeyers' ring, thyroid, and GI lymphomas) and 87 patients with extranodal non-gut-associated lymphoma (ENL). Survival and relapse data were assessed in multifactorial analysis to correct for previously identified other prognostic variables. GALT lymphomas (GALT-L) have a survival advantage compared with other ENL (P = .017) independent of stage and histology. A difference in distant relapse (DR) rate between GALT-L and other ENL (P = .0002) was also identified. The presentation site of localized extranodal NHL is predictive of clinical behavior and is an independent determinant of outcome. This may be an expression of lymphocytic origin and determinants of migration patterns.

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