scholarly journals Linkage analysis of a candidate region in Scandinavian sib pairs with multiple sclerosis reveals linkage to chromosome 17q

2000 ◽  
Vol 1 (7) ◽  
pp. 456-459 ◽  
Author(s):  
F Larsen ◽  
A Oturai ◽  
LP Ryder ◽  
HO Madsen ◽  
J Hillert ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Linkage Analysis ◽  
Candidate Region ◽  
Chromosome 17Q ◽  
Sib Pairs

scholarly journals Linkage analysis of multiple sclerosis with candidate region markers in Sardinian and Continental Italian families

1999 ◽  
Vol 7 (3) ◽  
pp. 377-385 ◽  
Author(s):  
Sandra D'Alfonso ◽  
Lorenza Nisticò ◽  
Patrizia Zavattari ◽  
Maria Giovanna Marrosu ◽  
Raffaele Murru ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Linkage Analysis ◽  
Candidate Region

Refining the linkage analysis on chromosome 10 in 449 sib-pairs with multiple sclerosis

2003 ◽  
Vol 143 (1-2) ◽  
pp. 31-38 ◽  
Author(s):  
Eva Åkesson ◽  
Francesca Coraddu ◽  
Maria Giovanna Marrosu ◽  
Luca Massacesi ◽  
Anke Hensiek ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Linkage Analysis ◽  
Chromosome 10 ◽  
Sib Pairs

Chromosome 14 Contains Determinants That Regulate Susceptibility to Theiler's Virus–Induced Demyelination in the Mouse

Genetics ◽  
1998 ◽  
Vol 148 (4) ◽  
pp. 1941-1949
Author(s):  
J-F Bureau ◽  
K M Drescher ◽  
L R Pease ◽  
T Vikoren ◽  
M Delcroix ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Major Histocompatibility Complex ◽  
Linkage Analysis ◽  
Demyelinating Disease ◽  
Theiler's Virus ◽  
Chromosome 14 ◽  
Virus Persistence ◽  
Histocompatibility Complex ◽  
Encephalomyelitis Virus ◽  
Two Peaks

Abstract Theiler's murine encephalomyelitis virus causes a chronic demyelinating disease in susceptible strains of mice that is similar to human multiple sclerosis. Several nonmajor histocompatibility complex–linked genes have been implicated as determinants of susceptibility or resistance to either demyelination or virus persistence. In this study, we used linkage analysis of major histocompatibility complex identical H-2d (DBA/2J × B10.D2) F2 intercross mice to identify loci associated with susceptibility to virus-induced demyelinating disease. In a 20-cM region on chromosome 14, we identified four markers, D14Mit54, D14Mit60, D14Mit61, and D14Mit90 that are significantly associated with demyelination. Because two peaks were identified, one near D14Mit54 and one near D14Mit90, it is possible that two loci in this region are involved in controlling demyelination.

Linkage analysis of 2q14-q23 and 5q32 with blood pressure quantitative traits in Chinese sib pairs

2003 ◽  
Vol 21 (2) ◽  
pp. 305-310 ◽  
Author(s):  
Dongliang Ge ◽  
Wenjie Yang ◽  
Jianfeng Huang ◽  
Cailiang Yao ◽  
Xisheng Xu ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Linkage Analysis ◽  
Quantitative Traits ◽  
Sib Pairs

Isolation of Microsatellites from the Spinal Muscular Atrophy (SMA) Candidate Region on Chromosome 5q and Linkage Analysis in Spanish SMA Families

1995 ◽  
Vol 3 (2) ◽  
pp. 96-101 ◽  
Author(s):  
Eladio Velascoa ◽  
Carmen Valero ◽  
Elena Garcia ◽  
Arancha de la Puente ◽  
Jesús Cruces ◽  
...  
Keyword(s):  
Linkage Analysis ◽  
Spinal Muscular Atrophy ◽  
Muscular Atrophy ◽  
Candidate Region ◽  
Chromosome 5Q

X-Linked Extension of the Revised Haseman-Elston Algorithm for Linkage Analysis in Sib Pairs

2003 ◽  
Vol 55 (2-3) ◽  
pp. 97-107 ◽  
Author(s):  
Howard Wiener ◽  
Robert C. Elston ◽  
Hemant K. Tiwari
Keyword(s):  
Linkage Analysis ◽  
Sib Pairs

scholarly journals Incorporating quantitative variables into linkage analysis using affected sib pairs

2007 ◽  
Vol 1 (S1) ◽  
Author(s):  
Yen-Feng Chiu ◽  
Jeng-Min Chiou ◽  
Yi-Shin Chen ◽  
Hui-Yi Kao ◽  
Fang-Chi Hsu
Keyword(s):  
Linkage Analysis ◽  
Affected Sib Pairs ◽  
Sib Pairs
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