Genetic Epidemiology
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scholarly journals Genome‐wide pleiotropy analysis identifies novel blood pressure variants and improves its polygenic risk scores

2022 ◽  
Author(s):  
Xiaofeng Zhu ◽  
Luke Zhu ◽  
Heming Wang ◽  
Richard S. Cooper ◽  
Aravinda Chakravarti
Keyword(s):  
Blood Pressure ◽  
Risk Scores ◽  
Polygenic Risk ◽  
Genome Wide

The eigen higher criticism and eigen Berk–Jones tests for multiple trait association studies based on GWAS summary statistics

2021 ◽  
Author(s):  
Wei Liu ◽  
Yuyang Xu ◽  
Anqi Wang ◽  
Tao Huang ◽  
Zhonghua Liu
Keyword(s):  
Association Studies ◽  
Summary Statistics ◽  
Multiple Trait ◽  
Trait Association ◽  
Higher Criticism

scholarly journals Issue Information

2021 ◽  
Vol 45 (8) ◽  
pp. 809-810

Full title: A large‐scale transcriptome‐wide association study (TWAS) of 10 blood cell phenotypes reveals complexities of TWAS fine‐mapping

2021 ◽  
Author(s):  
Amanda L. Tapia ◽  
Bryce T. Rowland ◽  
Jonathan D. Rosen ◽  
Michael Preuss ◽  
Kris Young ◽  
...  
Keyword(s):  
Blood Cell ◽  
Association Study ◽  
Fine Mapping ◽  
Large Scale ◽  
Cell Phenotypes

Precisely modeling zero‐inflated count phenotype for rare variants

2021 ◽  
Author(s):  
Qiao Fan ◽  
Shuming Sun ◽  
Yi‐Ju Li
Keyword(s):  
Rare Variants

scholarly journals Robust estimates of heritable coronary disease risk in individuals with type 2 diabetes

2021 ◽  
Author(s):  
Christopher Grace ◽  
Jemma C. Hopewell ◽  
Hugh Watkins ◽  
Martin Farrall ◽  
Anuj Goel
Keyword(s):  
Type 2 Diabetes ◽  
Coronary Disease ◽  
Disease Risk ◽  
Robust Estimates

Mendelian randomization in the multivariate general linear model framework

2021 ◽  
Author(s):  
Phillip H. Allman ◽  
Inmaculada Aban ◽  
Dustin M. Long ◽  
Amit Patki ◽  
Todd MacKenzie ◽  
...  
Keyword(s):  
Linear Model ◽  
Mendelian Randomization ◽  
General Linear Model ◽  
General Linear ◽  
Model Framework

Penalized mediation models for multivariate data

2021 ◽  
Author(s):  
Daniel J. Schaid ◽  
Ozan Dikilitas ◽  
Jason P. Sinnwell ◽  
Iftikhar J. Kullo
Keyword(s):  
Multivariate Data ◽  
Mediation Models

scholarly journals REHE: Fast variance components estimation for linear mixed models

2021 ◽  
Author(s):  
Kun Yue ◽  
Jing Ma ◽  
Timothy Thornton ◽  
Ali Shojaie
Keyword(s):  
Mixed Models ◽  
Variance Components ◽  
Linear Mixed Models ◽  
Variance Components Estimation
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