scholarly journals Treatment of spasticity with intrathecal Baclofen administration: long-term follow-up, review of 40 patients

Spinal Cord ◽  
2004 ◽  
Vol 42 (12) ◽  
pp. 686-693 ◽  
Author(s):  
R Plassat ◽  
B Perrouin Verbe ◽  
P Menei ◽  
D Menegalli ◽  
J F Mathé ◽  
...  
Keyword(s):  
Intrathecal Baclofen ◽  
Long Term Follow Up

Cautious Use of Intrathecal Baclofen in Walking Spastic Patients: Results on Long-term Follow-up

2006 ◽  
Vol 9 (2) ◽  
pp. 87-93 ◽  
Author(s):  
Ivano Dones ◽  
Vittoria Nazzi ◽  
Giovanni Tringali ◽  
Giovanni Broggi
Keyword(s):  
Intrathecal Baclofen ◽  
Long Term Follow Up

393 LONG TERM FOLLOW-UP AFTER CONTINUOUS INTRATHECAL BACLOFEN THERAPY FOR SEVERE SPASTICITY

2010 ◽  
Vol 4 (S1) ◽  
pp. 112-112
Author(s):  
E. Anastasiou ◽  
A. Tzortzopoulou ◽  
A. Alexandropoulou ◽  
K. Rizos ◽  
A. Karakosta ◽  
...  
Keyword(s):  
Intrathecal Baclofen ◽  
Intrathecal Baclofen Therapy ◽  
Severe Spasticity ◽  
Long Term Follow Up

Long-term follow-up on continuous intrathecal Baclofen therapy in non-ambulant children with intractable spastic Cerebral Palsy

2013 ◽  
Vol 17 (6) ◽  
pp. 639-644 ◽  
Author(s):  
Georges F. Vles ◽  
Dan L. Soudant ◽  
Marjanke A. Hoving ◽  
R. Jeroen Vermeulen ◽  
Laura A. Bonouvrié ◽  
...  
Keyword(s):  
Cerebral Palsy ◽  
Intrathecal Baclofen ◽  
Spastic Cerebral Palsy ◽  
Intrathecal Baclofen Therapy ◽  
Long Term Follow Up

Intrathecal baclofen administration for control of severe spinal spasticity: Functional improvement and long-term follow-up

1996 ◽  
Vol 77 (1) ◽  
pp. 35-39 ◽  
Author(s):  
Philippie Azouvi ◽  
Michèle Mane ◽  
Jean-Baptiste Thiebaut ◽  
Pierre Denys ◽  
Oivier Remy-Neris ◽  
...  
Keyword(s):  
Intrathecal Baclofen ◽  
Functional Improvement ◽  
Long Term Follow Up

Treatment of cerebral origin spasticity with continuous intrathecal baclofen delivered via an implantable pump: long-term follow-up review of 18 patients

1999 ◽  
Vol 91 (5) ◽  
pp. 733-736 ◽  
Author(s):  
Barry Rawicki
Keyword(s):  
Continuous Infusion ◽  
Nursing Care ◽  
Intrathecal Baclofen ◽  
Content Type ◽  
Implantable Pump ◽  
Severe Spasticity ◽  
Long Term Follow Up ◽  
Fine Print

Object. The goal of this study was to assess the long-term benefits of managing severe spasticity by using continuous infusion of intrathecal baclofen delivered via an implantable pump.Methods. Eighteen patients with severe spasticity of cerebral origin, who failed to respond adequately to more conservative treatments, have been treated with continuous infusion of intrathecal baclofen delivered via an implanted pump. Follow-up review of these patients has lasted between 12 months and 9 years. The patients have been assessed using a variety of tools. Seventeen have had a significant reduction in tone and all have benefited by a reduced need for nursing care or increased function or both.Conclusions. Long-term continuous infusion of intrathecal baclofen delivered via an implantable pump offers an effective method for dealing with otherwise intractable spasticity.

Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis
Keyword(s):  
Mental Health ◽  
Mental Disease ◽  
Brain Disorders ◽  
Social Stressors ◽  
Labor Education ◽  
Mental Diseases ◽  
Long Term Follow Up ◽  
Political Decisions

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.

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