Novel peptide isosteres that were designed to inhibit the binding of the HIV surface glycoprotein (gp120) to the T cell surface glycoprotein CD4

1998 ◽  
pp. 1627-1636 ◽  
Author(s):  
Michael G. B. Drew ◽  
Stephen Gorsuch ◽  
John Mann ◽  
Shimon Yoshida
Keyword(s):  
T Cell ◽  
Cell Surface ◽  
Surface Glycoprotein ◽  
Cell Surface Glycoprotein ◽  
Glycoprotein Gp120 ◽  
Peptide Isosteres

scholarly journals T-Cell Surface Glycoprotein CD3 Delta Chain

2020 ◽  
Author(s):  
Keyword(s):  
T Cell ◽  
Cell Surface ◽  
Surface Glycoprotein ◽  
Cell Surface Glycoprotein

Human T-cell leukaemia-associated cell surface glycoprotein gp37: Studies with three monoclonal antibodies and a rabbit antiserum

1986 ◽  
Vol 23 (6) ◽  
pp. 569-580 ◽  
Author(s):  
Ben K. Seon ◽  
Takashi Fukukawa ◽  
Anne L. Jackson ◽  
David Chervinsky ◽  
Cameron K. Tebbi ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
T Cell ◽  
Cell Surface ◽  
Rabbit Antiserum ◽  
Surface Glycoprotein ◽  
Cell Leukaemia ◽  
Cell Surface Glycoprotein ◽  
Human T Cell

scholarly journals Galectin-3 and Galectin-1 Bind Distinct Cell Surface Glycoprotein Receptors to Induce T Cell Death

2006 ◽  
Vol 176 (2) ◽  
pp. 778-789 ◽  
Author(s):  
Brianna N. Stillman ◽  
Daniel K. Hsu ◽  
Mabel Pang ◽  
C. Fred Brewer ◽  
Pauline Johnson ◽  
...  
Keyword(s):  
Cell Death ◽  
T Cell ◽  
Cell Surface ◽  
Surface Glycoprotein ◽  
Cell Surface Glycoprotein ◽  
Distinct Cell ◽  
Galectin 3

scholarly journals T-Cell Surface Glycoprotein CD5

2020 ◽  
Author(s):  
Keyword(s):  
T Cell ◽  
Cell Surface ◽  
Surface Glycoprotein ◽  
Cell Surface Glycoprotein

scholarly journals T-Cell Surface Glycoprotein CD3 Zeta Chain

2020 ◽  
Author(s):  
Keyword(s):  
T Cell ◽  
Cell Surface ◽  
Surface Glycoprotein ◽  
Cell Surface Glycoprotein ◽  
Zeta Chain

scholarly journals T-Cell Surface Glycoprotein CD3 Gamma Chain

2020 ◽  
Author(s):  
Keyword(s):  
T Cell ◽  
Cell Surface ◽  
Surface Glycoprotein ◽  
Gamma Chain ◽  
Cell Surface Glycoprotein

scholarly journals cell surface glycoproteins of murine cytotoxic T lymphocytes. I. T 145, a new cell surface glycoprotein selectively expressed on Ly 1-2(+) cytotoxic T lymphocytes

1978 ◽  
Vol 147 (5) ◽  
pp. 1418-1434 ◽  
Author(s):  
AK Kimura ◽  
H Wigzell
Keyword(s):  
T Cells ◽  
T Cell ◽  
T Lymphocytes ◽  
Cell Surface ◽  
Cytotoxic T Lymphocytes ◽  
Surface Glycoprotein ◽  
Cell Surface Glycoprotein ◽  
Cell Surface Glycoproteins ◽  
T Lymphoblasts ◽  
Surface Glycoproteins

T lymphocytes at various stages of maturation and differentiation have been isolated by cellular fractionation procedures and characterized by cell surface markers and functional assays, The cell surface glycoproteins of the various T-cell preparations have been selectively radiolabeled by the galactose oxidase-tritiated sodium borohydride technique and analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and fluorography. Details are presented on the appearance of a new cell surface glycoprotein (T 145), present on immunocompetent T lymphocytes after activation by either major histocompatibility complex alloantigens or by concanavalin A. The intensity of T 145 expression on T lymphoblasts is shown to be directly correlated in time and extent to the levels of cytotoxicity generated in a variety of T-cell activations. Specific enrichment procedures of purified populations of mixed leukocyte culture blasts have shown Ly 1(+)2(-) blasts to be T 145(-) and Ly 1(-)2(+) blasts to be strongly T 145(+). Similar enrichment procedures on normal peripheral T cells have failed to reveal any significant expression of T 145 on a highly enriched population of Ly 1(-)2(+) T cells, Further studies on the stability of T 145 expression after induction have shown it to be a more permanent-type differentiation structure whose expression is clearly not linked to the blast stage of activation. T 145 would thus appear to represent a membrane glycoprotein whose exclusive expression on T lymphoblasts is further restricted to a defined group of cells endowed with cytolytic activity and bearing the Ly phenotype Ly 1(-)2(+).

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