Microwave irradiation as an alternative to phase transfer catalysis in the liquid-solid phase, solvent-free C-alkylation of active methylene containing substrates

2006 ◽  
Vol 8 (12) ◽  
pp. 1073-1075 ◽  
Author(s):  
György Keglevich ◽  
Tibor Novák ◽  
László Vida ◽  
István Greiner
Keyword(s):  
Microwave Irradiation ◽  
Phase Transfer Catalysis ◽  
Phase Transfer ◽  
Solid Phase ◽  
Solvent Free ◽  
Active Methylene

scholarly journals Oxidation of Cyclohexanol and Cyclohexanone by Monochromate Ions in Organic Solvents and on Solvent Free Microwave Irradiation under Phase Transfer Catalysis - A Comparative Study

2021 ◽  
Vol 33 (9) ◽  
pp. 2033-2037
Author(s):  
P. Bashpa ◽  
P. Rajendran ◽  
K. Bijudas
Keyword(s):  
Microwave Irradiation ◽  
Organic Phase ◽  
Phase Transfer Catalysis ◽  
Phase Transfer ◽  
Mineral Acid ◽  
Solvent Free ◽  
High Yield ◽  
Catalysis Condition ◽  
Solvent Free Condition ◽  
Spectral Technique

Oxidation of cyclohexanol and cyclohexanone were carried out by acidified monochromate ions in ethyl acetate and toluene under phase transfer catalysis and also in solvent free condition under microwave irradiation. The extraction of monochromate ions from aqueous medium to organic phase was carried by employing various phase transfer catalysts in the presence of mineral acids. The effect of [catalyst] and [mineral acid] on extraction of monochromate from aqueous phase to organic phase was also studied. The product obtained, namely adipic acid obtained with both reactants was characterized by its melting point and infrared spectral technique. The reaction was over within 15 min with more than 85% yield at a temperature of 323 K under microwave irradiation where as it gave around 70% yield at 353 K within 150 min under phase transfer catalysis condition. The enhanced reaction rate and high yield of product substantiate the application of phase transfer catalytic technique under microwave irradiation for organic synthesis. A suitable mechanism for the oxidation of substrates by monochromate under phase transfer catalysis is also suggested.

Heterogeneous Phase Transfer Catalysis in Solid Phase Syntheses of Anth-Cyclic Tetrapeptides

2016 ◽  
Vol 81 (17) ◽  
pp. 8077-8081 ◽  
Author(s):  
Dongyue Xin ◽  
Jian Yuan ◽  
Kwok-Yin Wong ◽  
Kevin Burgess
Keyword(s):  
Phase Transfer Catalysis ◽  
Phase Transfer ◽  
Solid Phase ◽  
Cyclic Tetrapeptides ◽  
Heterogeneous Phase
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