Carrier protein substrates in cytochrome P450-catalysed oxidation

Metallomics ◽  
2011 ◽  
Vol 3 (4) ◽  
pp. 323 ◽  
Author(s):  
Max J. Cryle
Keyword(s):  
Cytochrome P450 ◽  
Carrier Protein ◽  
Protein Substrates ◽  
Catalysed Oxidation

scholarly journals Halogenation of glycopeptide antibiotics occurs at the amino acid level during non-ribosomal peptide synthesis

2017 ◽  
Vol 8 (9) ◽  
pp. 5992-6004 ◽  
Author(s):  
Tiia Kittilä ◽  
Claudia Kittel ◽  
Julien Tailhades ◽  
Diane Butz ◽  
Melanie Schoppet ◽  
...  
Keyword(s):  
Amino Acid ◽  
Peptide Synthesis ◽  
Acid Level ◽  
Amino Acid Level ◽  
Antibiotic Biosynthesis ◽  
Carrier Protein ◽  
Glycopeptide Antibiotics ◽  
Glycopeptide Antibiotic ◽  
Protein Substrates

Halogenase enzymes involved in glycopeptide antibiotic biosynthesis accept aminoacyl-carrier protein substrates.

scholarly journals Carrier Protein‐Free Enzymatic Biaryl Coupling in Arylomycin A2 Assembly and Structure of the Cytochrome P450 AryC

2021 ◽  
Author(s):  
Hülya Aldemir ◽  
Shuangjie Shu ◽  
Francoise Schaefers ◽  
Hanna Hong ◽  
René Richarz ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Carrier Protein ◽  
Biaryl Coupling

scholarly journals Carrier Protein-Free Chemo-Enzymatic Synthesis of Arylomycin A2 and Structural Characterization of the Cytochrome P450 AryC

2021 ◽  
Author(s):  
Tobias A. M. Gulder ◽  
Hülya Aldemir ◽  
Shuangjie Shu ◽  
Francoise Schaefers ◽  
Hanna Hong ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Structural Characterization ◽  
Enzymatic Synthesis ◽  
Carrier Protein

scholarly journals Carrier Protein‐Free Enzymatic Biaryl Coupling in Arylomycin A2 Assembly and Structure of the Cytochrome P450 AryC

2021 ◽  
Author(s):  
Hülya Aldemir ◽  
Shuangjie Shu ◽  
Francoise Schaefers ◽  
Hanna Hong ◽  
René Richarz ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Carrier Protein ◽  
Biaryl Coupling

Rapid access to glycopeptide antibiotic precursor peptides coupled with cytochrome P450-mediated catalysis: towards a biomimetic synthesis of glycopeptide antibiotics

2015 ◽  
Vol 13 (7) ◽  
pp. 2012-2021 ◽  
Author(s):  
Clara Brieke ◽  
Veronika Kratzig ◽  
Kristina Haslinger ◽  
Andreas Winkler ◽  
Max J. Cryle
Keyword(s):  
Cytochrome P450 ◽  
Biomimetic Synthesis ◽  
Carrier Protein ◽  
Cytochrome P450 Enzyme ◽  
Glycopeptide Antibiotics ◽  
Glycopeptide Antibiotic ◽  
Rapid Access ◽  
P450 Enzyme ◽  
Mediated Catalysis

One Cytochrome P450 enzyme performs the phenolic crosslinking of a range of chemically synthesized, carrier-protein loaded glycopeptide antibiotic precursor peptides.

Estradiol Regulation of Sterol Carrier Protein-2 Independent of Cytochrome P450 Side-Chain Cleavage Expression in the Rat Corpus Luteum*

Endocrinology ◽  
1989 ◽  
Vol 125 (3) ◽  
pp. 1337-1344 ◽  
Author(s):  
M. P. MCLEAN ◽  
T. K. PURYEAR ◽  
I. KHAN ◽  
S. AZHAR ◽  
J. T. BILLHEIMER ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Corpus Luteum ◽  
Side Chain ◽  
Carrier Protein ◽  
Sterol Carrier Protein ◽  
Side Chain Cleavage ◽  
Chain Cleavage ◽  
Sterol Carrier Protein 2

scholarly journals Comparison of human cytochrome P450 1A1-catalysed oxidation of benzo[a]pyrene in prokaryotic and eukaryotic expression systems

2017 ◽  
Vol 148 (11) ◽  
pp. 1959-1969 ◽  
Author(s):  
Marie Stiborová ◽  
Radek Indra ◽  
Michaela Moserová ◽  
Lucie Bořek-Dohalská ◽  
Petr Hodek ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Eukaryotic Expression ◽  
Expression Systems ◽  
Cytochrome P450 1A1 ◽  
Catalysed Oxidation ◽  
Human Cytochrome ◽  
Eukaryotic Expression Systems

scholarly journals Carrier Protein‐Free Enzymatic Biaryl Coupling in Arylomycin A2 Assembly and Structure of the Cytochrome P450 AryC

2021 ◽  
Author(s):  
Hülya Aldemir ◽  
Shuangjie Shu ◽  
Francoise Schaefers ◽  
Hanna Hong ◽  
René Richarz ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Carrier Protein ◽  
Biaryl Coupling

Molecular evolution of a cytochrome P450 for the synthesis of potential antidepressant (2R,6R)-hydroxynorketamine

2021 ◽  
Author(s):  
Ansgar Bokel ◽  
Michael C. Hutter ◽  
Vlada B. Urlacher
Keyword(s):  
Cytochrome P450 ◽  
Molecular Evolution ◽  
Cytochrome P450 Monooxygenase ◽  
P450 Monooxygenase ◽  
Effective Synthesis

Engineered cytochrome P450 monooxygenase CYP154E1 enables the effective synthesis of the potential antidepressant (2R,6R)-hydroxynorketamine via N-demethylation and regio- and stereoselective hydroxylation of (R)-ketamine.

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