Brønsted-acid catalyzed condensation-Michael reaction-Pictet–Spengler cyclization—highly stereoselective synthesis of indoloquinolizidines

RSC Advances ◽  
2011 ◽  
Vol 1 (1) ◽  
pp. 79 ◽  
Author(s):  
Magnus Rueping ◽  
Chandra M. R. Volla
Author(s):  
Xue-Jiao Lv ◽  
Yong-Chao Ming ◽  
Hui-Chun Wu ◽  
Yankai Liu

A Brønsted acid-catalyzed cascade acyclic N,O-hemiaminal formation/oxa-Michael reaction is developed for the synthesis of cis-2,6-disubstituted tetrahydropyrans bearing an exo amide group, that is, cyclic N,O-aminals. By using TsOH, various different...


2012 ◽  
Vol 67 (10) ◽  
pp. 1021-1029 ◽  
Author(s):  
Magnus Rueping ◽  
Stefan A. Moreth ◽  
Michael Bolte

The enantioselective synthesis of 2-aryl-substituted 2,3-dihydroquinolin-4-ones, a class of heterocyclic compounds with interesting biological activities, has been achieved through a Brønsted acidcatalyzed enantioselective intramolecular Michael addition. The products are available in moderate to high yields and with good enantioselectivities.


2017 ◽  
Vol 2017 (37) ◽  
pp. 5671-5678 ◽  
Author(s):  
Kiranmai Nayani ◽  
Radhika Cinsani ◽  
Anwar Hussaini SD ◽  
Prathama S. Mainkar ◽  
Srivari Chandrasekhar

2013 ◽  
Vol 125 (52) ◽  
pp. 14385-14389 ◽  
Author(s):  
Weijun Yang ◽  
Zhigen Yang ◽  
Lijun Xu ◽  
Lili Zhang ◽  
Xin Xu ◽  
...  

2020 ◽  
Vol 7 (18) ◽  
pp. 2664-2669
Author(s):  
Ni-Ni Zhou ◽  
Si-Si Ning ◽  
Lin-Qiang Li ◽  
Jie-Yun Zhang ◽  
Ming-Jin Fan ◽  
...  

The one-pot synthesis of dibenzo[a,f]azulen-12-ones has been established starting from o-propargyl alcohol benzaldehydes and alkynes.


2009 ◽  
Vol 50 (1) ◽  
pp. 48-50 ◽  
Author(s):  
Saleha Azad ◽  
Tomohiro Kobayashi ◽  
Keiji Nakano ◽  
Yoshiyasu Ichikawa ◽  
Hiyoshizo Kotsuki

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