Selective synthesis of secondary amines from nitriles using Pt nanowires as a catalyst

2014 ◽  
Vol 50 (26) ◽  
pp. 3512-3515 ◽  
Author(s):  
Shuanglong Lu ◽  
Jiaqing Wang ◽  
Xueqin Cao ◽  
Xinming Li ◽  
Hongwei Gu
Keyword(s):  
Secondary Amines ◽  
Selective Synthesis ◽  
Mild Conditions ◽  
Hydrogenation Of Nitriles ◽  
Pt Nanowires

A series of both symmetrical and unsymmetrical secondary amines are synthesized from hydrogenation of nitriles under mild conditions.

Catalyst-Dependent Selective Hydrogenation of Nitriles: Selective Synthesis of Tertiary and Secondary Amines

2017 ◽  
Vol 82 (20) ◽  
pp. 10939-10944 ◽  
Author(s):  
Yasunari Monguchi ◽  
Masahiro Mizuno ◽  
Tomohiro Ichikawa ◽  
Yuki Fujita ◽  
Eri Murakami ◽  
...  
Keyword(s):  
Selective Hydrogenation ◽  
Secondary Amines ◽  
Selective Synthesis ◽  
Hydrogenation Of Nitriles

scholarly journals Quasi Pd1Ni single-atom surface alloy catalyst enables hydrogenation of nitriles to secondary amines

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Hengwei Wang ◽  
Qiquan Luo ◽  
Wei Liu ◽  
Yue Lin ◽  
Qiaoqiao Guan ◽  
...  
Keyword(s):  
Building Blocks ◽  
Surface Alloy ◽  
Secondary Amines ◽  
Single Atom ◽  
Redox Potentials ◽  
Practical Applications ◽  
Mild Conditions ◽  
Metal Selectivity ◽  
High Yields ◽  
Hydrogenation Of Nitriles

Abstract Hydrogenation of nitriles represents as an atom-economic route to synthesize amines, crucial building blocks in fine chemicals. However, high redox potentials of nitriles render this approach to produce a mixture of amines, imines and low-value hydrogenolysis byproducts in general. Here we show that quasi atomic-dispersion of Pd within the outermost layer of Ni nanoparticles to form a Pd1Ni single-atom surface alloy structure maximizes the Pd utilization and breaks the strong metal-selectivity relations in benzonitrile hydrogenation, by prompting the yield of dibenzylamine drastically from ∼5 to 97% under mild conditions (80 °C; 0.6 MPa), and boosting an activity to about eight and four times higher than Pd and Pt standard catalysts, respectively. More importantly, the undesired carcinogenic toluene by-product is completely prohibited, rendering its practical applications, especially in pharmaceutical industry. Such strategy can be extended to a broad scope of nitriles with high yields of secondary amines under mild conditions.

ChemInform Abstract: Selective Synthesis of Secondary Amines from Nitriles Using Pt Nanowires as a Catalyst.

ChemInform ◽  
2014 ◽  
Vol 45 (33) ◽  
pp. no-no
Author(s):  
Shuanglong Lu ◽  
Jiaqing Wang ◽  
Xueqin Cao ◽  
Xinming Li ◽  
Hongwei Gu
Keyword(s):  
Secondary Amines ◽  
Selective Synthesis ◽  
Pt Nanowires

A Sequential Ugi-Smiles / Transition-Metal-Free Endo-Dig Conia-ene Cyclization: The Selective Synthesis of Saccharin Substituted 2,5-dihydropyrroles

2021 ◽  
Author(s):  
Hassan Seyrani ◽  
Sorour Ramezanpour ◽  
Aref Vaezghaemi ◽  
Farzad Kobarfard
Keyword(s):  
Transition Metal ◽  
Free Access ◽  
Selective Synthesis ◽  
Metal Free ◽  
Mild Conditions

A convenient, transition-metal-free access to a series of unprecedented saccharin substituted 2,5-dihydropyrroles is reported. This approach employs a post-Ugi-Smiles 5-endo-dig Conia-ene cyclization sequence in mild conditions while incorporating a series...

Ruthenium-Catalyzed Transfer Hydrogenation of Nitriles: Reduction and SubsequentN-Monoalkylation to Secondary Amines

2013 ◽  
Vol 2013 (18) ◽  
pp. 3671-3674 ◽  
Author(s):  
Svenja Werkmeister ◽  
Christoph Bornschein ◽  
Kathrin Junge ◽  
Matthias Beller
Keyword(s):  
Transfer Hydrogenation ◽  
Secondary Amines ◽  
Hydrogenation Of Nitriles

ChemInform Abstract: Ruthenium-Catalyzed Transfer Hydrogenation of Nitriles: Reduction and Subsequent N-Monoalkylation to Secondary Amines.

ChemInform ◽  
2013 ◽  
Vol 44 (45) ◽  
pp. no-no
Author(s):  
Svenja Werkmeister ◽  
Christoph Bornschein ◽  
Kathrin Junge ◽  
Matthias Beller
Keyword(s):  
Transfer Hydrogenation ◽  
Secondary Amines ◽  
Hydrogenation Of Nitriles

Titration syntheses of polyaminosubstituted phthalocyanines via nucleophilic aromatic substitutions on zinc(II) 1,2,3,4,8,9,10,11,15,16,17,18,22,23,24,25-hexadecafluorophthalocyanine

2007 ◽  
Vol 11 (07) ◽  
pp. 537-546 ◽  
Author(s):  
Clifford C. Leznoff ◽  
Annette Hiebert ◽  
Sibel Ok
Keyword(s):  
Amino Acids ◽  
Chain Length ◽  
Secondary Amines ◽  
Primary Amines ◽  
Tertiary Butyl ◽  
Butyl Esters ◽  
Mild Conditions ◽  
Nucleophilic Aromatic Substitutions

Primary amines, secondary amines and tertiary butyl esters of amino acids are used as nucleophiles with zinc(II) hexadecafluorophthalocyanine to provide mixtures of mono and disubstituted fluorinated phthalocyanines under mild conditions, or polyaminosubstituted phthalocyanines when using the amines as solvents. Diamines give cyclic substituted phthalocyanines, binuclear or trinuclear phthalocyanines or mixtures of both types, depending on the chain length or structure of the diamine.

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