Efficient synthesis of supported proline catalysts for asymmetric aldol reactions

2015 ◽  
Vol 5 (2) ◽  
pp. 690-696 ◽  
Author(s):  
A. A. Elmekawy ◽  
J. B. Sweeney ◽  
D. R. Brown
Keyword(s):  
High Activity ◽  
Aldol Reaction ◽  
Single Step ◽  
Aldol Reactions ◽  
Efficient Synthesis ◽  
Asymmetric Aldol ◽  
Mcm 41

l-Proline is grafted onto silica (MCM-41) in a single step and shows high activity and enantioselectivity in an aldol reaction.

Alternating chiral selectivity of aldol reactions under the confined space of mesoporous silica

2015 ◽  
Vol 51 (96) ◽  
pp. 17116-17119 ◽  
Author(s):  
Chewei Yeh ◽  
Yan-Ru Sun ◽  
Shing-Jong Huang ◽  
Yeun-Min Tsai ◽  
Soofin Cheng
Keyword(s):  
Mesoporous Silica ◽  
Aldol Reaction ◽  
Recyclable Catalyst ◽  
Aldol Reactions ◽  
Water Medium ◽  
Confined Space ◽  
Asymmetric Aldol ◽  
Co Catalysts ◽  
Asymmetric Aldol Reaction ◽  
Chiral Selectivity

The chiral selectivities were altered and high diastereo- and enantio-selectivities of the products were obtained in water medium without adding acid co-catalysts when a primary–tertiary diamine catalyst was immobilized on mesoporous SBA-15 to form a recyclable catalyst for the direct asymmetric aldol reaction of cyclohexanone with p-nitrobenzaldehyde.

scholarly journals Development of fructose-1,6-bisphosphate aldolase enzyme peptide mimics as biocatalysts in direct asymmetric aldol reactions

RSC Advances ◽  
2021 ◽  
Vol 11 (58) ◽  
pp. 36670-36681
Author(s):  
Thabo Peme ◽  
Dean Brady ◽  
Wanyama Juma ◽  
Maya Makatini
Keyword(s):  
Aldol Reaction ◽  
Aldol Reactions ◽  
Peptide Mimics ◽  
Structural Motifs ◽  
Asymmetric Aldol ◽  
Asymmetric Aldol Reaction ◽  
Fructose 1,6 Bisphosphate

Novel asymmetric aldol reaction catalysing fructose-1,6-bisphosphate aldolase peptide mimics with secondary structural motifs.

ChemInform Abstract: A Direct Catalytic Asymmetric Aldol Reaction of α-Sulfanyl Lactones: Efficient Synthesis of SPT Inhibitors.

ChemInform ◽  
2012 ◽  
Vol 43 (37) ◽  
pp. no-no
Author(s):  
Sho Takechi ◽  
Shigeo Yasuda ◽  
Naoya Kumagai ◽  
Masakatsu Shibasaki
Keyword(s):  
Aldol Reaction ◽  
Efficient Synthesis ◽  
Asymmetric Aldol ◽  
Asymmetric Aldol Reaction ◽  
Catalytic Asymmetric

Aerobic photooxidative direct asymmetric aldol reactions of benzyl alcohols using water as the solvent

RSC Advances ◽  
2015 ◽  
Vol 5 (49) ◽  
pp. 39539-39543 ◽  
Author(s):  
A. Fujiya ◽  
T. Nobuta ◽  
E. Yamaguchi ◽  
N. Tada ◽  
T. Miura ◽  
...  
Keyword(s):  
Aldol Reaction ◽  
Aldol Reactions ◽  
Asymmetric Aldol ◽  
Benzyl Alcohols ◽  
Asymmetric Aldol Reaction

We report an aerobic photooxidative direct asymmetric aldol reaction using water as the solvent.

Asymmetric aldol reaction organocatalyzed by bifunctional N-prolyl sulfinamides under solvent-free conditions

RSC Advances ◽  
2014 ◽  
Vol 4 (51) ◽  
pp. 26563-26568 ◽  
Author(s):  
Wen Wan ◽  
Wei Gao ◽  
Guobin Ma ◽  
Lei Ma ◽  
Fan Wang ◽  
...  
Keyword(s):  
Aldol Reaction ◽  
Solvent Free ◽  
Aldol Reactions ◽  
Matching Effect ◽  
Asymmetric Aldol ◽  
Solvent Free Conditions ◽  
Asymmetric Aldol Reaction

Chiral bifunctional N-prolyl sulfinamide and its TFA salts were synthesized and applied in asymmetric aldol reactions under solvent-free conditions. The aldol adducts were obtained with high to excellent yields, enantioselectivities and diastereoselectivities. A matching effect between chiral proline and sulfinamide moieties was observed for the catalysts.

Boron-Mediated Aldol Reaction of Carboxylic Esters:  Complementary Anti- and Syn-Selective Asymmetric Aldol Reactions

2002 ◽  
Vol 67 (15) ◽  
pp. 5250-5256 ◽  
Author(s):  
Tadashi Inoue ◽  
Ji-Feng Liu ◽  
Dana C. Buske ◽  
Atsushi Abiko
Keyword(s):  
Aldol Reaction ◽  
Aldol Reactions ◽  
Asymmetric Aldol ◽  
Carboxylic Esters
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