Enantioselective one-pot synthesis of dihydroquinolones via BINOL-derived Lewis acid catalysis
2014 ◽
Vol 12
(28)
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pp. 5094-5097
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A high-yielding and diastereoselective route to biologically significant 2-aryl- and 2-alkyl-3-amido dihydroquinolones has been developed in up to 90 : 10 e.r. by employing a novel Lewis acidic BINOL-derived copper(ii) catalyst.