High-yielding sequential one-pot synthesis of chiral and achiral α-substituted acrylates via a metal-free reductive coupling reaction
2014 ◽
Vol 12
(29)
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pp. 5400-5406
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Keyword(s):
One Pot
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A variety of chiral and achiral α-substituted acrylates were furnished in very good yields with excellent selectivity by using an organocatalytic reductive coupling reaction (TCRA) followed by an Eschenmoser methylenation.