Terminal protection of small molecule-linked ssDNA for label-free and highly sensitive colorimetric detection of folate receptor biomarkers

RSC Advances ◽  
2015 ◽  
Vol 5 (8) ◽  
pp. 6100-6105 ◽  
Author(s):  
Xue Gong ◽  
Wenjiao Zhou ◽  
Yaqin Chai ◽  
Yun Xiang ◽  
Ruo Yuan

Protection of ssDNA from digesting by Exo I generates amplified color transition for label-free and sensitive detection of folate receptors.

Nanoscale ◽  
2014 ◽  
Vol 6 (6) ◽  
pp. 3055-3058 ◽  
Author(s):  
Xinjian Yang ◽  
Zhiqiang Gao

By combining terminal protection of small molecule (folate)-capped DNA probes, exonuclease III signal amplification and gold nanoparticles, we developed a simple and label-free colorimetric assay for highly sensitive detection of folate receptor.


The Analyst ◽  
2015 ◽  
Vol 140 (4) ◽  
pp. 1260-1264 ◽  
Author(s):  
Yanhong Zhu ◽  
Guangfeng Wang ◽  
Liang Sha ◽  
Yuwei Qiu ◽  
Hong Jiang ◽  
...  

Development of strategies for the sensitive and selective detection of the folate receptor (FR) that are simple and low cost is of great importance for assessing cancer therapeutics due to its crucial role in physiological, pharmacological and pathological processes.


2016 ◽  
Vol 40 (11) ◽  
pp. 9046-9053 ◽  
Author(s):  
Sudeshna Chandra ◽  
Christian Gäbler ◽  
Christian Schliebe ◽  
Heinrich Lang ◽  
Dhirendra Bahadur

An amperometric immunosensor based on a redox active ferrocenyl end-grafted PAMAM dendrimer provides highly sensitive detection of immunoglobulin, down to 2 ng mL−1.


Nanoscale ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 5466-5473 ◽  
Author(s):  
Attasith Parnsubsakul ◽  
Sukunya Oaew ◽  
Werasak Surareungchai

Recyclable zwitterionic peptide-capped AuNPs for highly sensitive detection of Ni2+.


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