Application of inductively coupled plasma mass spectrometry in the study of apoptosis: determination of caspase-3 using a gold nanoparticle tag

The Analyst ◽  
2016 ◽  
Vol 141 (3) ◽  
pp. 926-933 ◽  
Author(s):  
Zhengru Liu ◽  
Beibei Chen ◽  
Man He ◽  
Xing Zhang ◽  
Han Wang ◽  
...  

A simple, fast and sensitive immunoassay for caspase-3 is established by using inductively coupled plasma mass spectrometry (ICP-MS) detection and signal enhancement gold nanoparticle (Au-NP) labelling of the secondary antibody (IgG).

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