scholarly journals Amino acids as chiral anionic ligands for ruthenium based asymmetric olefin metathesis

2015 ◽  
Vol 51 (18) ◽  
pp. 3870-3873 ◽  
Author(s):  
Elisa Ivry ◽  
Amos Ben-Asuly ◽  
Israel Goldberg ◽  
N. Gabriel Lemcoff
Keyword(s):  
Amino Acids ◽  
Ligand Exchange ◽  
Olefin Metathesis ◽  
Anionic Ligand ◽  
Anionic Ligands ◽  
Metathesis Reactions

Anionic ligand exchange by amino acids readily produce chiral ruthenium benzylidenes that catalyze asymmetric olefin metathesis reactions.

scholarly journals Mechanistic insights of anionic ligand exchange and fullerene reduction with magnesium(i) compounds

2019 ◽  
Vol 48 (45) ◽  
pp. 16936-16942 ◽  
Author(s):  
Samuel R. Lawrence ◽  
David B. Cordes ◽  
Alexandra M. Z. Slawin ◽  
Andreas Stasch
Keyword(s):  
Ligand Exchange ◽  
Associative Mechanism ◽  
Anionic Ligand ◽  
Anionic Ligands

Exchange of anionic ligands on the Mg22+ ion via an associative mechanism can be facile and depends on ligand sterics and shape.

Sulfur-Chelated Ruthenium Olefin Metathesis Catalysts

Synlett ◽  
2020 ◽  
Author(s):  
N. Gabriel Lemcoff ◽  
Noy B. Nechmad
Keyword(s):  
3D Printing ◽  
Olefin Metathesis ◽  
Historical Development ◽  
Unique Feature ◽  
Anionic Ligands ◽  
Metathesis Reactions ◽  
Light Stimuli ◽  
Metathesis Catalysts

This Account summarizes the historical development of latent sulfur-chelated ruthenium precatalysts from the Lemcoff group’s perspective. The most unique feature of this family of complexes is that they appear in the more stable cis-dichloro configuration, which is latent towards olefin metathesis reactions. Activation of the precatalyst, brought about by isomerization from the cis-dihalo to the trans-dihalo forms, can be achieved either by thermal or light stimuli. Modifications of the ligand sphere bestows unique properties upon the catalysts, which have been used in diverse applications, from 3D printing of metathesis polymers to orthogonally divergent synthetic pathways.1 Introduction2 Effect of Sulfur Substituents3 Effect of Benzylidene Ligands4 Effect of the NHC Ligands5 Effect of the Anionic Ligands6 Conclusions

Pentacoordinate Ruthenium(II) Catecholthiolate and Mercaptophenolate Catalysts for Olefin Metathesis: Anionic Ligand Exchange and Ease of Initiation

2016 ◽  
Vol 35 (22) ◽  
pp. 3878-3892 ◽  
Author(s):  
Malte S. Mikus ◽  
Sebastian Torker ◽  
Chaofan Xu ◽  
Bo Li ◽  
Amir H. Hoveyda
Keyword(s):  
Ligand Exchange ◽  
Olefin Metathesis ◽  
Anionic Ligand

Catalytic Carbonyl-Olefin Metathesis of Aliphatic Ketones: Iron(III) HomoDimers as Lewis Acidic Superelectrophiles

2018 ◽  
Author(s):  
Haley Albright ◽  
Paul S. Riehl ◽  
Christopher C. McAtee ◽  
Jolene P. Reid ◽  
Jacob R. Ludwig ◽  
...  
Keyword(s):  
Lewis Acid ◽  
Olefin Metathesis ◽  
Acid Activation ◽  
Lewis Acid Catalysts ◽  
Distinct Mode ◽  
Aliphatic Ketones ◽  
Carbon Carbon Bond ◽  
Metathesis Reactions ◽  
Acid Catalyzed

<div>Catalytic carbonyl-olefin metathesis reactions have recently been developed as a powerful tool for carbon-carbon bond</div><div>formation. However, currently available synthetic protocols rely exclusively on aryl ketone substrates while the corresponding aliphatic analogs remain elusive. We herein report the development of Lewis acid-catalyzed carbonyl-olefin ring-closing metathesis reactions for aliphatic ketones. Mechanistic investigations are consistent with a distinct mode of activation relying on the in situ formation of a homobimetallic singly-bridged iron(III)-dimer as the active catalytic species. These “superelectrophiles” function as more powerful Lewis acid catalysts that form upon association of individual iron(III)-monomers. While this mode of Lewis acid activation has previously been postulated to exist, it has not yet been applied in a catalytic setting. The insights presented are expected to enable further advancement in Lewis acid catalysis by building upon the activation principle of “superelectrophiles” and broaden the current scope of catalytic carbonyl-olefin metathesis reactions.</div>

scholarly journals Modification of proteins using olefin metathesis

2020 ◽  
Vol 4 (4) ◽  
pp. 1040-1051 ◽  
Author(s):  
Marco S. Messina ◽  
Heather D. Maynard
Keyword(s):  
Small Molecules ◽  
Olefin Metathesis ◽  
Aqueous Media ◽  
Metathesis Reactions ◽  
P Proteins

Proteins are modified with small molecules and polymers via olefin metathesis reactions in aqueous media.

Ligand-exchange chromatography of α-trifluoromethyl-α-amino acids on chiral sorbents

1990 ◽  
Vol 511 ◽  
pp. 115-121 ◽  
Author(s):  
S.V. Galushko ◽  
I.P. Shishkina ◽  
V.A. Solshonok ◽  
V.P. Kukhar
Keyword(s):  
Amino Acids ◽  
Ligand Exchange ◽  
Exchange Chromatography ◽  
Ligand Exchange Chromatography
Sign in / Sign up

Export Citation Format

Share Document