Tandem hydrogenation and condensation of fluorinated α,β-unsaturated ketones with primary amines, catalyzed by nickel

2015 ◽  
Vol 44 (35) ◽  
pp. 15653-15663 ◽  
Author(s):  
Nahury Castellanos-Blanco ◽  
Marcos Flores-Alamo ◽  
Juventino J. García
Keyword(s):  
Catalytic System ◽  
Transfer Hydrogenation ◽  
Primary Amines ◽  
Unsaturated Ketones ◽  
Phosphine Complexes ◽  
Hydrogen Donors ◽  
Nickel Phosphine

A simple homogeneous catalytic system based on nickel phosphine complexes has been developed for the transfer hydrogenation and condensation of α,β-unsaturated ketones to yield saturated ones and saturated imines using primary amines as hydrogen donors.

Iridium-catalyzed Transfer Hydrogenation for Construction of Quinolines from 2-Aminobenzyl Alcohols with Enones in Water

Synthesis ◽  
2021 ◽  
Author(s):  
Nian hua Luo ◽  
HongLing Shui ◽  
Yuhong Zhong ◽  
Jiu-Zhong Huang ◽  
Renshi Luo
Keyword(s):  
Functional Groups ◽  
Catalytic System ◽  
Control Experiment ◽  
High Efficiency ◽  
Transfer Hydrogenation ◽  
Environmentally Benign ◽  
Iridium Complex ◽  
Unsaturated Ketones ◽  
Scale Control

Herein, we describe a method for the synthesis of functionalized quinolines from 2-aminobenzyl alcohols with α, β-unsaturated ketones. This method exhibits various functional groups tolerance, high-efficiency, environmentally benign and can be performed on a gram scale. Control experiment suggests this transformation is accomplished by iridium complex-catalyzed transfer hydrogenation, which is then followed by the Friedländer cyclization. The results display the alkali is essential for the high selectivities of this catalytic system.

A Hantzsch Amido Dihydropyridine as a Transfer Hydrogenation Reagent for α,β-Unsaturated Ketones

2016 ◽  
Vol 81 (9) ◽  
pp. 3528-3532 ◽  
Author(s):  
Scott A. Van Arman ◽  
Austin J. Zimmet ◽  
Ian E. Murray
Keyword(s):  
Transfer Hydrogenation ◽  
Unsaturated Ketones

Selective catalytic transfer hydrogenation of nitriles to primary amines using Pd/C

2014 ◽  
Vol 4 (3) ◽  
pp. 629 ◽  
Author(s):  
Marcelo Vilches-Herrera ◽  
Svenja Werkmeister ◽  
Kathrin Junge ◽  
Armin Börner ◽  
Matthias Beller
Keyword(s):  
Transfer Hydrogenation ◽  
Primary Amines ◽  
Catalytic Transfer Hydrogenation ◽  
Catalytic Transfer ◽  
Hydrogenation Of Nitriles

scholarly journals Bis-NHC–Ag/Pd(OAc)2 Catalytic System Catalyzed Transfer Hydrogenation Reaction

Catalysts ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 8
Author(s):  
Hui-Ju Chen ◽  
Chien-Cheng Chiu ◽  
Tsui Wang ◽  
Dong-Sheng Lee ◽  
Ta-Jung Lu
Keyword(s):  
Functional Groups ◽  
Catalytic System ◽  
High Efficiency ◽  
Aqueous Media ◽  
Hydrogenation Reaction ◽  
Transfer Hydrogenation ◽  
Terminal Alkynes ◽  
Wide Range ◽  
Transfer Hydrogenation Reaction

The bis-NHC–Ag/Pd(OAc)2 catalytic system (NHC = N-heterocyclic carbene), a combination of bis-NHC–Ag complex and Pd(OAc)2, was found to be a smart catalyst in the Pd-catalyzed transfer hydrogenation of various functionalized arenes and internal/terminal alkynes. The catalytic system demonstrated high efficiency for the reduction of a wide range of various functional groups such as carbonyls, alkynes, olefins, and nitro groups in good to excellent yields and high chemoselectivity for the reduction of functional groups. In addition, the protocol was successfully exploited to stereoselectivity for the transformation of alkynes to alkenes in aqueous media under air. This methodology successfully provided an alternative useful protocol for reducing various functional groups and a simple operational protocol for transfer hydrogenation.

Catalytic Hydrogenolysis of Biphenylene with Platinum, Palladium, and Nickel Phosphine Complexes

1998 ◽  
Vol 17 (22) ◽  
pp. 4784-4794 ◽  
Author(s):  
Brian L. Edelbach ◽  
David A. Vicic ◽  
Rene J. Lachicotte ◽  
William D. Jones
Keyword(s):  
Phosphine Complexes ◽  
Catalytic Hydrogenolysis ◽  
Nickel Phosphine

scholarly journals Asymmetric transfer hydrogenation of prochiral ketones catalyzed by aminosulfonamide-ruthenium complexes in ionic liquid

2011 ◽  
Vol 9 (1) ◽  
pp. 175-179 ◽  
Author(s):  
Zhongqiang Zhou ◽  
Yong Sun ◽  
Aiqing Zhang
Keyword(s):  
Ionic Liquid ◽  
Catalytic System ◽  
Ruthenium Complexes ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Prochiral Ketones

AbstractChiral aminosulfonamides containing imidazolium group were used as ligands for the ruthenium(II)-catalyzed asymmetric transfer hydrogenation of prochiral ketones in ionic liquid, affording good to excellent conversions and enantiomeric excesses. The catalytic system could be easily recovered and reused several times.

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