pH-Sensitive graphene oxide/sodium alginate/polyacrylamide nanocomposite semi-IPN hydrogel with improved mechanical strength

RSC Advances ◽  
2015 ◽  
Vol 5 (108) ◽  
pp. 89083-89091 ◽  
Author(s):  
Huijuan Zhang ◽  
Xianjuan Pang ◽  
Yuan Qi

A pH-sensitive and mechanically strong graphene oxide/sodium alginate/polyacrylamide nanocomposite semi-IPN hydrogel was designed and prepared. The composite semi-IPN hydrogel showed superior mechanical strength and pH-dependent swelling behavior.

RSC Advances ◽  
2014 ◽  
Vol 4 (84) ◽  
pp. 44600-44609 ◽  
Author(s):  
Huijuan Zhang ◽  
Dandan Zhai ◽  
Yang He

A ternary GO/PAM/CMC nanocomposite hydrogel was fabricated by introducing GO into PAM/CMC hydrogels followed by ionically crosslinking of Al3+. The compressive strength of the ternary hydrogel was dramatically enhanced with the incorporation of only 1.6 wt% GO sheets.


2020 ◽  
Vol 193 ◽  
pp. 108010
Author(s):  
Beom-Gon Cho ◽  
Shalik Ram Joshi ◽  
Jaekyo Lee ◽  
Young-Bin Park ◽  
Gun-Ho Kim

The Analyst ◽  
2013 ◽  
Vol 138 (15) ◽  
pp. 4393 ◽  
Author(s):  
Minjia Hao ◽  
Na Liu ◽  
Zhanfang Ma

Author(s):  
Dianxin Li ◽  
Peng Zhang ◽  
Yiqing Yang ◽  
Yuqi Huang ◽  
Tao Li ◽  
...  

Author(s):  
Farah Amanina Mohd Zin ◽  
An’amt Mohamed Noor ◽  
Wan Nurshafeera Wan Mohd Nasri ◽  
Nurul Natasya Rosli ◽  
Nur Aqilah Buniamin ◽  
...  

2008 ◽  
Vol 183 (5) ◽  
pp. 865-879 ◽  
Author(s):  
Christian Frantz ◽  
Gabriela Barreiro ◽  
Laura Dominguez ◽  
Xiaoming Chen ◽  
Robert Eddy ◽  
...  

Newly generated actin free barbed ends at the front of motile cells provide sites for actin filament assembly driving membrane protrusion. Growth factors induce a rapid biphasic increase in actin free barbed ends, and we found both phases absent in fibroblasts lacking H+ efflux by the Na-H exchanger NHE1. The first phase is restored by expression of mutant cofilin-H133A but not unphosphorylated cofilin-S3A. Constant pH molecular dynamics simulations and nuclear magnetic resonance (NMR) reveal pH-sensitive structural changes in the cofilin C-terminal filamentous actin binding site dependent on His133. However, cofilin-H133A retains pH-sensitive changes in NMR spectra and severing activity in vitro, which suggests that it has a more complex behavior in cells. Cofilin activity is inhibited by phosphoinositide binding, and we found that phosphoinositide binding is pH-dependent for wild-type cofilin, with decreased binding at a higher pH. In contrast, phosphoinositide binding by cofilin-H133A is attenuated and pH insensitive. These data suggest a molecular mechanism whereby cofilin acts as a pH sensor to mediate a pH-dependent actin filament dynamics.


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