Magnetic chondroitin targeted nanoparticles for dual targeting of montelukast in prevention of in-stent restenosis

RSC Advances ◽  
2016 ◽  
Vol 6 (15) ◽  
pp. 12337-12347 ◽  
Author(s):  
Jaleh Varshosaz ◽  
Shaghayegh Haghjooy Javanmard ◽  
Sahel Soghrati ◽  
Behshid Behdadfar
Keyword(s):  
Endothelial Cells ◽  
Magnetic Nanoparticles ◽  
Chondroitin Sulfate ◽  
Targeted Nanoparticles ◽  
Stent Restenosis ◽  
Dual Targeting ◽  
Rosin Gum ◽  
In Stent Restenosis

Magnetic nanoparticles and sodium montelukast encapsulated in rosin gum nanoparticles were targeted by chondroitin sulfate coated on their surface. They showed adhesion to endothelial cells and efficiently suppressed the VCAM-1 expression.

Favorable manipulation of macrophage/endothelial cell functionality and their cross-talk on silicon-doped titania nanotube arrays

Nanoscale ◽  
2019 ◽  
Vol 11 (13) ◽  
pp. 5920-5931 ◽  
Author(s):  
Long Bai ◽  
Yanlian Liu ◽  
Xiangyu Zhang ◽  
Xiaobo Huang ◽  
Xiaohong Yao ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Endothelial Cell ◽  
Nanotube Arrays ◽  
Inflammatory Reactions ◽  
Stent Restenosis ◽  
Titania Nanotube Arrays ◽  
Silicon Doped ◽  
Doped Titania ◽  
Cell Functionality ◽  
In Stent Restenosis

Inflammatory reactions and the functionality of endothelial cells (ECs) on the surfaces of coronary stents are critical in the prevention of in-stent restenosis and subsequent neoatherosclerosis.

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