Peptidylation for the determination of low-molecular-weight compounds by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

The Analyst ◽  
2016 ◽  
Vol 141 (11) ◽  
pp. 3259-3265 ◽  
Author(s):  
Feng Tang ◽  
Si-Ying Cen ◽  
Huan He ◽  
Yi Liu ◽  
Bi-Feng Yuan ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Laser Desorption ◽  
Low Molecular Weight ◽  
Laser Desorption Ionization ◽  
Ionization Time ◽  
Flight Mass Spectrometry ◽  
Low Molecular Weight Compounds ◽  
Matrix Assisted Laser ◽  
Matrix Assisted Laser Desorption

A universal peptide-based derivatization (peptidylation) strategy for the sensitive detection of low-molecular-weight compounds by MALDI-TOF-MS was developed.

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