Functional gold nanoparticles coupled with laser desorption ionization mass spectrometry for bioanalysis

2016 ◽  
Vol 8 (46) ◽  
pp. 8123-8133 ◽  
Author(s):  
Binesh Unnikrishnan ◽  
Chia-Yin Chang ◽  
Han-Wei Chu ◽  
Anisha Anand ◽  
Chih-Ching Huang

Monitoring of surface ligand and gold cluster ions produced by pulsed-laser-induced desorption/ionization of gold nanoparticles enables the transduction and amplification of mass signals for biosensing and bioimaging applications.

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