Q-SA√ESS: a methodology to help solvent selection for pharmaceutical manufacture at the early process development stage

2016 ◽  
Vol 18 (24) ◽  
pp. 6564-6572 ◽  
Author(s):  
Valerio Isoni ◽  
Loretta L. Wong ◽  
Hsien H. Khoo ◽  
Iskandar Halim ◽  
Paul Sharratt

A practicable, LCA based methodology has been developed to evaluate the sustainability implications of solvent selection during early process development for a batch manufacturing process for an API.

2021 ◽  
Author(s):  
Amir Al Ghatta ◽  
James D. E. T. Wilton-Ely ◽  
Jason P. Hallett

Process simulations allow the evaluation of the emissions and selling price for the production of the key monomer FDCA based on different feedstocks and solvent systems, alongside considerations of safety and current process development.


2021 ◽  
Author(s):  
Alexander James Doolin ◽  
Rhys Gareth Charles ◽  
Catherine S. P. De Castro ◽  
Rodrigo Garcia Rodriguez ◽  
Emmanuel Vincent Péan ◽  
...  

An approach for screening solvent systems for PSCs to substitute REACH restricted DMF with no loss in device performance.


2013 ◽  
Vol 37 ◽  
pp. 257-264 ◽  
Author(s):  
Juan Salazar ◽  
Urmila Diwekar ◽  
Kevin Joback ◽  
Adam H. Berger ◽  
Abhoyjit S. Bhown

Author(s):  
Bahadır Tunaboylu ◽  
Biset Toprak ◽  
Ahmet Korhan Binark ◽  
Osman Öztürk ◽  
Selim Zaim

2022 ◽  
Vol 162 ◽  
pp. 106568
Author(s):  
Markus Enekvist ◽  
Xiaodong Liang ◽  
Xiangping Zhang ◽  
Kim Dam-Johansen ◽  
Georgios M. Kontogeorgis

2004 ◽  
Vol 40 (2) ◽  
pp. 133-145 ◽  
Author(s):  
V.Y. Dindore ◽  
D.W.F. Brilman ◽  
F.H. Geuzebroek ◽  
G.F. Versteeg

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