Gas-phase synthesis of 3-carboethoxy-quinolin-4-ones. A comprehensive computational mechanistic study to uncover the dark side of the Gould–Jacobs reaction

RSC Advances ◽  
2016 ◽  
Vol 6 (87) ◽  
pp. 83973-83981 ◽  
Author(s):  
Ivana Malvacio ◽  
E. Laura Moyano ◽  
D. Mariano A. Vera

A set of 3-carboethoxy-quinolin-4-ones were synthesized from diethyl 2-((arylamino)methylene) malonates through a Gould–Jacobs cyclization using flash vacuum pyrolysis (FVP). A detailed mechanistic study was done using DFT and Coupled Clusters models.

ChemInform ◽  
2001 ◽  
Vol 32 (8) ◽  
pp. no-no
Author(s):  
A. Zak ◽  
Y. Feldman ◽  
V. Alperovich ◽  
R. Rosentsveig ◽  
R. Tenne

Nano Letters ◽  
2008 ◽  
Vol 8 (7) ◽  
pp. 2012-2016 ◽  
Author(s):  
Albert Dato ◽  
Velimir Radmilovic ◽  
Zonghoon Lee ◽  
Jonathan Phillips ◽  
Michael Frenklach

2007 ◽  
Vol 119 (37) ◽  
pp. 7178-7181 ◽  
Author(s):  
Richard A. J. O'Hair ◽  
Tom Waters ◽  
Benjamin Cao

2008 ◽  
Vol 53 (12) ◽  
pp. 1878-1884 ◽  
Author(s):  
V. V. Utochnikova ◽  
O. V. Kotova ◽  
E. M. Shchukina ◽  
S. V. Eliseeva ◽  
N. P. Kuz’mina

Synthesis ◽  
2014 ◽  
Vol 47 (02) ◽  
pp. 242-248 ◽  
Author(s):  
Alison Hulme ◽  
Martha Mackay ◽  
Andrew Nortcliffe ◽  
Hamish McNab

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