Near-infrared fluorescent probes for the detection of glutathione and their application in the fluorescence imaging of living cells and tumor-bearing mice

2018 ◽  
Vol 6 (17) ◽  
pp. 2541-2546 ◽  
Author(s):  
Dayoung Lee ◽  
Keunsoo Jeong ◽  
Xiao Luo ◽  
Gayoung Kim ◽  
Youjun Yang ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Fluorescent Probes ◽  
Near Infrared ◽  
Living Cells ◽  
Tumor Bearing

We present two new cyanine-based NIR fluorescent probes for imaging GSH in living cells and tumor-bearing mice.

Fluorinated near-infrared fluorescent probes for specific detection of Hg2+ in an aqueous medium and mitochondria of living cells

2017 ◽  
Vol 41 (17) ◽  
pp. 8899-8904 ◽  
Author(s):  
Lei Long ◽  
Xu Tan ◽  
Shenglin Luo ◽  
Chunmeng Shi
Keyword(s):  
Aqueous Medium ◽  
Fluorescent Probe ◽  
Fluorescent Probes ◽  
Near Infrared ◽  
Living Cells ◽  
Specific Detection

A near-infrared fluorescent probe (IR-DFT) could be used for specifically and sensitively detecting Hg2+ in mitochondria of living cells.

Clinical use of organic near-infrared fluorescent contrast agents in image-guided oncologic procedures and its potential in veterinary oncology

2018 ◽  
Vol 183 (11) ◽  
pp. 354-354 ◽  
Author(s):  
Sophie Favril ◽  
Eline Abma ◽  
Francesco Blasi ◽  
Emmelie Stock ◽  
Nausikaa Devriendt ◽  
...  
Keyword(s):  
Fluorescence Imaging ◽  
Fluorescent Probes ◽  
Near Infrared ◽  
Sentinel Lymph Node Mapping ◽  
Cost Effective ◽  
Surgical Oncology ◽  
Great Promise ◽  
Lymph Node Mapping ◽  
Nir Light ◽  
Nir Fluorescence

One of the major challenges in surgical oncology is the intraoperative discrimination of tumoural versus healthy tissue. Until today, surgeons rely on visual inspection and palpation to define the tumoural margins during surgery and, unfortunately, for various cancer types, the local recurrence rate thus remains unacceptably high. Near-infrared (NIR) fluorescence imaging is an optical imaging technique that can provide real-time preoperative and intraoperative information after administration of a fluorescent probe that emits NIR light once exposed to a NIR light source. This technique is safe, cost-effective and technically easy. Several NIR fluorescent probes are currently studied for their ability to highlight neoplastic cells. In addition, NIR fluorescence imaging holds great promise for sentinel lymph node mapping. The aim of this manuscript is to provide a literature review of the current organic NIR fluorescent probes tested in the light of human oncology and to introduce fluorescence imaging as a valuable asset in veterinary oncology.

Far-red to near infrared analyte-responsive fluorescent probes based on organic fluorophore platforms for fluorescence imaging

2013 ◽  
Vol 42 (2) ◽  
pp. 622-661 ◽  
Author(s):  
Lin Yuan ◽  
Weiying Lin ◽  
Kaibo Zheng ◽  
Longwei He ◽  
Weimin Huang
Keyword(s):  
Fluorescence Imaging ◽  
Fluorescent Probes ◽  
Near Infrared ◽  
Organic Fluorophore

Sensitive Near-Infrared Fluorescent Probes for Thiols Based on SeN Bond Cleavage: Imaging in Living Cells and Tissues

2012 ◽  
Vol 18 (36) ◽  
pp. 11343-11349 ◽  
Author(s):  
Rui Wang ◽  
Lingxin Chen ◽  
Ping Liu ◽  
Qin Zhang ◽  
Yunqing Wang
Keyword(s):  
Fluorescent Probes ◽  
Near Infrared ◽  
Bond Cleavage ◽  
Living Cells

Inhibitor structure-guided design and synthesis of near-infrared fluorescent probes for monoamine oxidase A (MAO-A) and its application in living cells and in vivo

2019 ◽  
Vol 55 (17) ◽  
pp. 2477-2480 ◽  
Author(s):  
Zhengmin Yang ◽  
Wenxiu Li ◽  
Hua Chen ◽  
Qingyuan Mo ◽  
Jun Li ◽  
...  
Keyword(s):  
Monoamine Oxidase ◽  
Fluorescent Probes ◽  
Near Infrared ◽  
Living Cells ◽  
Monoamine Oxidase A ◽  
Specific Detection ◽  
Design And Synthesis ◽  
Mao A ◽  
In Cells

A series of near-infrared fluorescent probes based on inhibitor (clorgyline) structure-guided design were synthesized for the specific detection of MAO-A in cells and in vivo.

pH-activatable near-infrared fluorescent probes for detection of lysosomal pH inside living cells

2014 ◽  
Vol 2 (28) ◽  
pp. 4500-4508 ◽  
Author(s):  
Giri K. Vegesna ◽  
Jagadeesh Janjanam ◽  
Jianheng Bi ◽  
Fen-Tair Luo ◽  
Jingtuo Zhang ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Near Infrared ◽  
Living Cells ◽  
Lysosomal Ph

Four near-infrared fluorescent probes have been synthesized, characterized, and evaluated for detection of lysosomal pH inside living cells.

Near-Infrared Two-Photon Fluorescent Chemodosimeter Based on Rhodamine-BODIPY for Mercury Ion Fluorescence Imaging in Living Cells

2017 ◽  
Vol 2 (31) ◽  
pp. 9970-9976 ◽  
Author(s):  
Baoxing Shen ◽  
Ying Qian ◽  
Zhengqing Qi ◽  
Changgui Lu ◽  
Yiping Cui
Keyword(s):  
Fluorescence Imaging ◽  
Near Infrared ◽  
Living Cells ◽  
Mercury Ion ◽  
Two Photon ◽  
Fluorescent Chemodosimeter

Near-infrared fluorescent probes based on piperazine-functionalized BODIPY dyes for sensitive detection of lysosomal pH

2015 ◽  
Vol 3 (10) ◽  
pp. 2173-2184 ◽  
Author(s):  
Jingtuo Zhang ◽  
Mu Yang ◽  
Cong Li ◽  
Nethaniah Dorh ◽  
Fei Xie ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Near Infrared ◽  
Living Cells ◽  
Sensitive Detection ◽  
Lysosomal Ph

Three BODIPY-based near-infrared fluorescent probes have been synthesized, characterized, and evaluated for the sensing and imaging of lysosomal pH inside living cells.

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