Nano-sized paramagnetic and fluorescent fluorinated carbon fiber with high NIR absorbance for cancer chemo-photothermal therapy

2018 ◽  
Vol 6 (19) ◽  
pp. 3068-3077 ◽  
Author(s):  
Peiwei Gong ◽  
Lihua Guo ◽  
Minghui Pang ◽  
Dandan Wang ◽  
Lu Sun ◽  
...  

We report a novel strategy to synthesize nano-sized, water-soluble and functionalized fluorinated carbon fiber oxide with high fluorescence, paramagnetism and NIR absorption for cancer chemo-photothermal therapy.

2017 ◽  
Vol 5 (30) ◽  
pp. 6128-6137 ◽  
Author(s):  
Lu Sun ◽  
Peiwei Gong ◽  
Xicheng Liu ◽  
Minghui Pang ◽  
Meng Tian ◽  
...  

We report a novel strategy to synthesize nanosized water-soluble fluorinated carbon fiber oxide (FCO) that doubles as an effective photothermal agent and a high cargo payload platform for an anticancer drug.


2019 ◽  
Vol 244 ◽  
pp. 39-42 ◽  
Author(s):  
Lei Zhang ◽  
Mengzhen Wang ◽  
Fei Kong ◽  
Shuohan Li ◽  
Gangyan Dai ◽  
...  

2008 ◽  
Vol 82 (12) ◽  
pp. 2126-2133
Author(s):  
N. A. Zubareva ◽  
T. M. Roshchina ◽  
T. D. Khokhlova ◽  
N. K. Shoniya

2019 ◽  
Vol 55 (73) ◽  
pp. 10940-10943 ◽  
Author(s):  
Yongchao Yan ◽  
Hao Fu ◽  
Jian Wang ◽  
Chuanrong Chen ◽  
Qi Wang ◽  
...  

A photo-stable and reversible pH-responsive phenazine dye displayed an obvious NIR absorption in a weak acid environment of tumor. The dye assembled into nanoparticles was developed for photoacoustic imaging-guided photothermal therapy in mice.


2020 ◽  
Vol 60 (8) ◽  
pp. 2008-2022
Author(s):  
Maja D. Markovic ◽  
Vesna V. Panic ◽  
Sanja I. Seslija ◽  
Ana D. Milivojevic ◽  
Pavle M. Spasojevic ◽  
...  

2018 ◽  
Vol 193 ◽  
pp. 03049
Author(s):  
Vadim Solov'ev ◽  
Marsel’ Nurtdinov ◽  
Il’ya Kukhar

The research was conducted in order to determine the effect of the polymer additive on the adhesion between the fiber and the cement-sand matrix, since the involvement stage of the composite fiber material directly depends on the adhesion value between these dissimilar components. Throughout the study, the issue at stake was to determine the optimal method for adhesion increasing to assess its effectiveness, and also to carry out an experiment and obtain actual numerical change values of the adhesion to carbon fiber (the assessment was made considering changes of the strength parameters). According to the results of conducted testings, the tensile strength during the bend almost wasn’t affected in resin-injected samples with the amount of fiber of 1 and 3% (increments of 12.7 and 15.7%, respectively). Despite this, the combined application of a resin with the same amount of fiber gave the increments of 34 and 20%, respectively. Conclusions are drawn about the prospects of polymer additives usage in carbon fiber reinforced concrete. The mechanism of increasing the carbon fiber involvement in the composite behavior is considered, the positive effect is confirmed by the study of the chemical processes that arise during the interaction of fiber and water-soluble resin.


2019 ◽  
Vol 23 (11n12) ◽  
pp. 1195-1215 ◽  
Author(s):  
Ariana Yett ◽  
Linda Yingqi Lin ◽  
Dana Beseiso ◽  
Joanne Miao ◽  
Liliya A. Yatsunyk

[Formula: see text]-methyl mesoporphyrin IX (NMM) is a water-soluble, non-symmetric porphyrin with excellent optical properties and unparalleled selectivity for G-quadruplex (GQ) DNA. G-quadruplexes are non-canonical DNA structures formed by guanine-rich sequences. They are implicated in genomic stability, longevity, and cancer. The ability of NMM to selectively recognize GQ structures makes it a valuable scaffold for designing novel GQ binders. In this review, we survey the literature describing the GQ-binding properties of NMM as well as its wide utility in chemistry and biology. We start with the discovery of the GQ-binding properties of NMM and the development of NMM-binding aptamers. We then discuss the optical properties of NMM, focusing on the light-switch effect — high fluorescence of NMM induced upon its binding to GQ DNA. Additionally, we examine the affinity and selectivity of NMM for GQs, as well as its ability to stabilize GQ structures and favor parallel GQ conformations. Furthermore, a portion of the review is dedicated to the applications of NMM-GQ complexes as biosensors for heavy metals, small molecules ([Formula: see text] ATP and pesticides), DNA, and proteins. Finally and importantly, we discuss the utility of NMM as a probe to investigate the roles of GQs in biological processes.


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