silica microparticles
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Cells ◽  
2022 ◽  
Vol 11 (2) ◽  
pp. 226
Author(s):  
Sabrina Colafarina ◽  
Piero Di Carlo ◽  
Osvaldo Zarivi ◽  
Massimo Aloisi ◽  
Alessandra Di Serafino ◽  
...  

Indoor air pollutants (IAP), which can pose a serious risk to human health, include biological pollutants, nitric oxide (NO), nitrogen dioxide (NO2), volatile organic compounds (VOC), sulfur dioxide (SO2), carbon monoxide (CO), carbon dioxide (CO2), silica, metals, radon, and particulate matter (PM). The aim of our work is to conduct a multidisciplinary study of fine silica particles (<2.5 μm) in the presence or absence of ozone (O3), and evaluate their potential cytotoxicity using MTS, micronucleus, and the comet test in two cell lines. We analyzed A549 (human basal alveolar epithelial cell adenocarcinoma) and Hs27 (human normal fibroblasts) exposed to dynamic conditions by an IRC simulator under ozone flow (120 ppb) and in the presence of silica particles (40 μg/h). The viability of A549 and Hs27 cells at 48 and 72 h of exposure to silica or silica/ozone decreases, except at 72 h in Hs27 treated with silica/ozone. The micronucleus and comet tests showed a significant increase in the number of micronuclei and the % of DNA in the queue, compared to the control, in both lines in all treatments, even if in different cell times/types. We found that silica alone or with more O3 causes more pronounced genotoxic effects in A549 tumor cells than in normal Hs27 fibroblasts.


2022 ◽  
Vol 30 ◽  
pp. 096739112110633
Author(s):  
Deepak SampathKumar ◽  
Thirumalaikumarasamy Duraisamy ◽  
Thirumal Pattabi ◽  
AshokKumar Mohankumar

At present, puncture resistance and rheological performance of shear thickening fluid (STF) is an essential design requirement for a soft armour material (target sample). The target sample is prepared with a dip and dry process of STF impregnated woven polypropylene (PP) fabric. These samples were tested and compared with neat PP fabric. The penetration depth of target samples is highly sensitive to the coefficient of friction between the indenter’s nose shape geometry and the target sample. The STF is prepared by mechanical dispersion of synthesized microsphere silica microparticles at a volume fraction of 57% in polyethylene glycol (400 g/mol). The rheological response indicates that the prepared concentration of silica microparticles in the STF suspension is observed to have a better shear thickening effect. The viscosity of suspension is highly sensitive to silica aspect ratio, volume fraction and particle size distribution in this work. Tensile tests along with puncture resistance with different indenter nose shapes geometry (hemispherical, elliptical, flat and conical) have been performed in the present study. Results indicate that the energy absorption is more with the hemispherical indenter and less with that of the conical indenter, which is attributed to the minimum surface area of contact as compared to all other indenters. A total of 16 number of fabricated target samples with various coating thicknesses of STF impregnated fabrics achieved the desired tensile strength, modulus and puncture resistance.


Nanomaterials ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3354
Author(s):  
Alvaro Lafraya ◽  
Cristina Prieto ◽  
Maria Pardo-Figuerez ◽  
Alberto Chiva ◽  
Jose M. Lagaron

In the current work, a super-repellent biopaper suitable for food contact applications was developed. To do this, three different kinds of biopolymers, namely polylactide (PLA), poly(ε-caprolactone) (PCL), poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV), and hydrophobic silica microparticles (SiO2), were sequentially processed by electrohydrodynamic processing (EDHP). As a first step, the ultrathin biopolymer fibers were deposited onto a commercial food contact cellulose paper by electrospinning and, thereafter, the nanostructured silica was sequentially electrosprayed. The multilayer coated papers were annealed at different temperatures to promote adhesion between the layers and enhance the super-repellent properties. The developed coatings were characterized in terms of morphology, permeance to water vapor, adhesion, mechanical resistance, and contact and sliding angle. The resultant multilayer biopapers presented a hierarchical micro/nanostructured surface with an apparent water contact angle (WCA) higher than 155° and sliding angle (SA) lower than 10° for all the tested biopolymers used. Among the different multilayer approaches, it was observed that the paper/PHBV/SiO2 showed the best performance, in terms of water vapor permeance; resistance after the tape peeling-off test; and food super-repelling properties to water, yogurt, and custard. Overall, this study presents the successful generation of super-repellent biopapers coated with PLA, PCL, or PHBV along with hydrophobic silica microparticles and its effectiveness for easy emptying food packaging applications to reduce food waste.


2021 ◽  
pp. 112778
Author(s):  
Cristina Fuentes ◽  
Ana Fuentes ◽  
Hugh J. Byrne ◽  
José Manuel Barat ◽  
María José Ruiz

Author(s):  
Il-Seop Jang ◽  
Ji Yeon Park ◽  
Hayoung Park ◽  
Yang Mo Gu ◽  
Jin Hyung Lee ◽  
...  

Langmuir ◽  
2021 ◽  
Author(s):  
Guoqiang Tang ◽  
Congcong Wang ◽  
Kai Zhang ◽  
Yao Wang ◽  
Bai Yang

Nanomedicine ◽  
2021 ◽  
Vol 16 (23) ◽  
pp. 2061-2074
Author(s):  
Caterina Di Sano ◽  
Claudia D’Anna ◽  
Antonino Scurria ◽  
Claudia Lino ◽  
Mario Pagliaro ◽  
...  

Aim: To assess whether Omeg@Silica microparticles – fish oil from anchovy fillet leftovers (AnchoisOil) encapsulated within mesoporous silica particles – are effective in promoting antitumor effects in lung cancer cells. Methods: Three human non-small-cell lung cancer cell lines (A549, Colo 699 and SK-MES-1) were used. Cells were treated with AnchoisOil dispersed in ethanol (10 and 15 μg/ml) or encapsulated in silica and further formulated in aqueous ethanol. Cell cycle, reactive oxygen species, mitochondrial stress and long-term proliferation were assessed. Results & conclusion: Omeg@Silica microparticles were more effective than fish oil in increasing reactive oxygen species and mitochondrial damage, and in altering the cell cycle and reducing cell proliferation, in lung cancer cells. These in vitro antitumor effects of Omeg@Silica support its investigation in lung cancer therapy.


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