Use multiscale simulation to explore the effects of the homodimerizations between different conformation states on the activation and allosteric pathway for the μ-opioid receptor

2018 ◽  
Vol 20 (19) ◽  
pp. 13485-13496 ◽  
Author(s):  
Xi Zhang ◽  
Yuan Yuan ◽  
Longrong Wang ◽  
Yanzhi Guo ◽  
Menglong Li ◽  
...  
Keyword(s):  
Opioid Receptor ◽  
Multiscale Simulation ◽  
Gpcr Dimer ◽  
Μ Opioid Receptor ◽  
Allosteric Pathway

Using multiscale simulation to explore the activation of a GPCR dimer.

FUNCTIONAL INTERACTIONS OF PERTUSSIS TOXIN-SENSITIVE G-PROTEINS WITH THE TRANSFECTED μ-OPIOID RECEPTOR IN RAT 1 FIBROBLASTS

Analgesia ◽  
1995 ◽  
Vol 1 (4) ◽  
pp. 438-441
Author(s):  
Zafiroula Georgoussi ◽  
Ian Mullaney ◽  
Alan Wise ◽  
Craig Carr ◽  
Graeme Milligan
Keyword(s):  
G Proteins ◽  
Opioid Receptor ◽  
Pertussis Toxin ◽  
Functional Interactions ◽  
Μ Opioid Receptor

Modulation of μ-opioid receptor desensitization in peripheral sensory neurons by phosphoinositide 3-kinase γ

Neuroscience ◽  
2010 ◽  
Vol 169 (1) ◽  
pp. 449-454 ◽  
Author(s):  
C. König ◽  
O. Gavrilova-Ruch ◽  
G. Segond von Banchet ◽  
R. Bauer ◽  
M. Grün ◽  
...  
Keyword(s):  
Opioid Receptor ◽  
Sensory Neurons ◽  
Receptor Desensitization ◽  
Peripheral Sensory Neurons ◽  
Μ Opioid Receptor ◽  
Phosphoinositide 3 Kinase ◽  
Peripheral Sensory

Blockade of lipopolysaccharide-induced fever by a μ-opioid receptor-selective antagonist in rats

2000 ◽  
Vol 401 (2) ◽  
pp. 161-165 ◽  
Author(s):  
Khalid Benamar ◽  
Li Xin ◽  
Ellen B Geller ◽  
Martin W Adler
Keyword(s):  
Opioid Receptor ◽  
Selective Antagonist ◽  
Μ Opioid Receptor

scholarly journals The region in the μ opioid receptor conferring selectivity for sufentanil over the δ receptor is different from that over the κ receptor

FEBS Letters ◽  
1996 ◽  
Vol 384 (2) ◽  
pp. 198-202 ◽  
Author(s):  
Jinmin Zhu ◽  
Ji-Chun Xue ◽  
Ping-Yee Law ◽  
Patricia A. Claude ◽  
Lai-Yi Luo ◽  
...  
Keyword(s):  
Opioid Receptor ◽  
Μ Opioid Receptor ◽  
Κ Receptor
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