Separation and characterization of KRas proteins and tryptic peptides using enhanced-fluidity liquid chromatography tandem mass spectrometry

The Analyst ◽  
2019 ◽  
Vol 144 (21) ◽  
pp. 6270-6275
Author(s):  
Juan Bian ◽  
Susan V. Olesik
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Reversed Phase ◽  
Liquid Chromatography Mass Spectrometry ◽  
Reversed Phase Liquid Chromatography ◽  
Ras Protein ◽  
Chromatography Tandem Mass Spectrometry ◽  
Liquid Chromatography Tandem Mass ◽  
Phase Liquid

A sensitive method for detecting the K-Ras protein and its mutation was developed using enhanced-fluidity, reversed-phase liquid chromatography-mass spectrometry.

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