scholarly journals Metabolic mapping with plasmonic nanoparticle assemblies

The Analyst ◽  
2020 ◽  
Vol 145 (7) ◽  
pp. 2586-2594 ◽  
Author(s):  
Nguyen H. Le ◽  
Gang Ye ◽  
Chun Peng ◽  
Jennifer I. L. Chen
Keyword(s):  
Gold Nanoparticle ◽  
Single Cells ◽  
Metabolic Mapping ◽  
Plasmonic Nanoparticle ◽  
Nanoparticle Assemblies

Discrete plasmonic gold nanoparticle assemblies rapidly detect ATP in single cells and microenvironments without labelling, extraction, purification or separation.

scholarly journals Multiplexed and single-cell detection of microRNA with plasmonic nanoparticle assemblies

2021 ◽  
Author(s):  
Gurbrinder Ghotra ◽  
Nguyen Le ◽  
Heyam Hayder ◽  
Chun Peng ◽  
Jennifer I. L. Chen
Keyword(s):  
Nucleic Acid ◽  
Single Cell ◽  
Low Cost ◽  
Single Cells ◽  
Cell Detection ◽  
Label Free ◽  
Plasmonic Nanoparticle ◽  
Nanoparticle Assemblies ◽  
Single Cell Detection ◽  
Target Binding

We present a label-free, low cost and miniatured biosensing platform based on the disassembly of core-satellite plasmonic nanoparticle assemblies. The rapid and selective detection of an exemplary nucleic acid biomarker, has-miRNA-210-3p, was achieved via the strand displacement nucleic acid reaction. Target binding leads to dehybridization of the DNA linkers and changes in the scattering properties of nanostructures as monitored by darkfield microscopy. We demonstrate the ability to detect microRNA expunged from single cells and the potential to multiplex discrete assemblies to enable diverse biological applicability. The work may help translate the applicability of microRNA as diagnostic biomarkers, quantitate their abundance in the microenvironment, and facilitate the study of their correlation or causation to other biomolecules at the single-cell level.

Visualization of Localized Intense Optical Fields in Single Gold−Nanoparticle Assemblies and Ultrasensitive Raman Active Sites

Nano Letters ◽  
2006 ◽  
Vol 6 (10) ◽  
pp. 2173-2176 ◽  
Author(s):  
Kohei Imura ◽  
Hiromi Okamoto ◽  
Mohammad K. Hossain ◽  
Masahiro Kitajima
Keyword(s):  
Gold Nanoparticle ◽  
Active Sites ◽  
Optical Fields ◽  
Nanoparticle Assemblies

What Controls the Optical Properties of DNA-Linked Gold Nanoparticle Assemblies?

2000 ◽  
Vol 122 (19) ◽  
pp. 4640-4650 ◽  
Author(s):  
James J. Storhoff ◽  
Anne A. Lazarides ◽  
Robert C. Mucic ◽  
Chad A. Mirkin ◽  
Robert L. Letsinger ◽  
...  
Keyword(s):  
Optical Properties ◽  
Gold Nanoparticle ◽  
Nanoparticle Assemblies

What Controls the Optical Properties of DNA-Linked Gold Nanoparticle Assemblies?*

2020 ◽  
pp. 293-324
Author(s):  
James J. Storhoff ◽  
Anne A. Lazarides ◽  
Robert C. Mucic ◽  
Chad A. Mirkin ◽  
Robert L. Letsinger ◽  
...  
Keyword(s):  
Optical Properties ◽  
Gold Nanoparticle ◽  
Nanoparticle Assemblies

Plasmonic control of drug release efficiency in agarose gel loaded with gold nanoparticle assemblies

2021 ◽  
pp. 253-264
Author(s):  
Luca Moretti ◽  
Andrea Mazzanti ◽  
Arianna Rossetti ◽  
Andrea Schirato ◽  
Laura Polito ◽  
...  
Keyword(s):  
Drug Release ◽  
Gold Nanoparticle ◽  
Agarose Gel ◽  
Nanoparticle Assemblies

Photocatalytic Properties of TiO2 Composites Immobilized with Gold Nanoparticle Assemblies Using the Streptavidin–Biotin Interaction

Langmuir ◽  
2016 ◽  
Vol 32 (25) ◽  
pp. 6459-6467 ◽  
Author(s):  
Hirofumi Harada ◽  
Akira Onoda ◽  
Taro Uematsu ◽  
Susumu Kuwabata ◽  
Takashi Hayashi
Keyword(s):  
Gold Nanoparticle ◽  
Photocatalytic Properties ◽  
Nanoparticle Assemblies
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