Ratiometric emission NIR-fluorescent probe for the detection of lysosomal pH in living cells and in vivo

2019 ◽  
Vol 43 (34) ◽  
pp. 13363-13370 ◽  
Author(s):  
Weifen Niu ◽  
Juan Jia ◽  
Junkai Li ◽  
Chao Zhang ◽  
Keming Yun

A lysosome-targeted ratiometric emission NIR-fluorescent probe for monitoring the lysosomal pH changes at a cellular level and LPS-mediated inflammation in vivo.

2017 ◽  
Vol 5 (5) ◽  
pp. 988-995 ◽  
Author(s):  
Baoli Dong ◽  
Xuezhen Song ◽  
Xiuqi Kong ◽  
Chao Wang ◽  
Nan Zhang ◽  
...  

Lysosomal pH is closely related to the metastasis and apoptosis of cancer cells.


2018 ◽  
Vol 266 ◽  
pp. 416-421 ◽  
Author(s):  
Dayoung Lee ◽  
K.M.K. Swamy ◽  
Joohee Hong ◽  
Songyi Lee ◽  
Juyoung Yoon

2020 ◽  
Vol 8 (7) ◽  
pp. 1466-1471 ◽  
Author(s):  
Xiaodong Wang ◽  
Li Fan ◽  
Yubin Wang ◽  
Caihong Zhang ◽  
Wenting Liang ◽  
...  

We report a red-emission fluorescent pH probe (RML) for visual monitoring of the lysosomal pH changes during autophagy in living cells.


The Analyst ◽  
2020 ◽  
Vol 145 (21) ◽  
pp. 7018-7024 ◽  
Author(s):  
Xiaodong Wang ◽  
Li Fan ◽  
Xiaoran Zhang ◽  
Qi Zan ◽  
Wenjuan Dong ◽  
...  

We report a red-emission pH fluorescent probe (MSO) for visual monitoring of lysosomal pH changes during mitophagy and cell apoptosis in living cells.


2019 ◽  
Vol 290 ◽  
pp. 79-86 ◽  
Author(s):  
Xiongjie Zhao ◽  
Chao Wang ◽  
Gangqiang Yuan ◽  
Haiyuan Ding ◽  
Liyi Zhou ◽  
...  

2017 ◽  
Vol 53 (26) ◽  
pp. 3701-3704 ◽  
Author(s):  
Shahi Imam Reja ◽  
Muskan Gupta ◽  
Neha Gupta ◽  
Vandana Bhalla ◽  
Puja Ohri ◽  
...  

A lysosome targetable naphthalimide based fluorescent probe has been designed and synthesized for selective imaging of H2O2 in different cells, tissues and in vivo models.


2021 ◽  
Author(s):  
Hong-Min Lv ◽  
Zi-Ke Jiang ◽  
Jing Wang ◽  
Tao Wang ◽  
Xiao-Nan Zhang ◽  
...  

The sensing mechanism toward Hcy/Cys is realized based on the condensation reaction, which breaks CN to form a thiazolidine adduct.


2020 ◽  
Vol 44 (28) ◽  
pp. 12107-12112 ◽  
Author(s):  
Yunyan Zhang ◽  
Xiuqi Kong ◽  
Yonghe Tang ◽  
Min Li ◽  
Yaguang Yin ◽  
...  

A novel ratiometric fluorescent probe, Hcy-CO, with long-wavelength emission was developed for visualizing CO in living cells and zebrafish.


2020 ◽  
Vol 19 (9) ◽  
pp. 1230-1235
Author(s):  
Sufang Ma ◽  
Xueyi Sun ◽  
Qiang Yu ◽  
Rui Liu ◽  
Zhonglin Lu ◽  
...  

A new fluorescent probe for nitric oxide (NO) was prepared, which shows great potential for understanding the biological roles of NO in vivo.


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