scholarly journals Evaluation of non-targeting, C- or N-pH (low) insertion peptide modified superparamagnetic iron oxide nanoclusters for selective MRI of liver tumors and their potential toxicity in cirrhosis

RSC Advances ◽  
2019 ◽  
Vol 9 (25) ◽  
pp. 14051-14059
Author(s):  
Abdulrahman Ahmed Mahmood ◽  
Jianqi Zhang ◽  
Rufang Liao ◽  
Xiwei Pan ◽  
Dan Xu ◽  
...  

The acid-responsive pHLIP modified SPION as an MRI contrast agent for liver cancer diagnosis requires the validation of both the tumor-specific enhancement and a safe profile in cirrhosis.

Nanoscale ◽  
2014 ◽  
Vol 6 (16) ◽  
pp. 9646-9654 ◽  
Author(s):  
Daniel Nordmeyer ◽  
Patrick Stumpf ◽  
Dominic Gröger ◽  
Andreas Hofmann ◽  
Sven Enders ◽  
...  

Superparamagnetic iron oxide nanoparticles with a dendritic polyglycerol (dPG) sulfate strongly bind to L- and P-selectin. Shielding of leukocytes reduces cell extravasation and binding to endothelial cells indicate inflammation specificity and thus, applicability as selective MRI contrast agent.


2021 ◽  
Vol Volume 16 ◽  
pp. 201-211
Author(s):  
Li-Hua Deng ◽  
Hai Jiang ◽  
Fu-Lin Lu ◽  
Han-Wei Wang ◽  
Yu Pu ◽  
...  

RSC Advances ◽  
2012 ◽  
Vol 2 (16) ◽  
pp. 6655 ◽  
Author(s):  
Durga P. Acharya ◽  
Bradford A. Moffat ◽  
Anastasios Polyzos ◽  
Lynne Waddington ◽  
Greg Coia ◽  
...  

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