Copper-catalyzed cascade cyclization reaction of 3-aminocyclobutenones with electron-deficient internal alkynes: synthesis of fully substituted indoles

2020 ◽  
Vol 56 (68) ◽  
pp. 9815-9818 ◽  
Author(s):  
Yang Yu ◽  
Xin-Yu Wang ◽  
Ju-Yin Peng ◽  
Tao Liu ◽  
Yu-Long Zhao
Keyword(s):  
Single Step ◽  
Cyclization Reaction ◽  
New Method ◽  
Cascade Cyclization ◽  
Internal Alkynes

A novel copper-catalyzed cascade cyclization reaction of 3-aminocyclobutenones with electron-deficient internal alkynes has been developed. This reaction provides a new method for the synthesis of fully substituted indoles by formation of four new bonds and two rings in a single step.

ChemInform Abstract: Superbase-Promoted Selective Cascade Cyclization Reaction of 1,5-Diketones with Acetylenes to Methylene-6,8-dioxabicyclo[3.2.1]octanes.

ChemInform ◽  
2013 ◽  
Vol 44 (37) ◽  
pp. no-no
Author(s):  
Elena Yu. Schmidt ◽  
Ivan A. Bidusenko ◽  
Nadezhda I. Protsuk ◽  
Igor A. Ushakov ◽  
Boris A. Trofimov
Keyword(s):  
Cyclization Reaction ◽  
Cascade Cyclization

Diverse privileged N-polycyclic skeletons accessed from a metal-free cascade cyclization reaction

2021 ◽  
Vol 19 (37) ◽  
pp. 8086-8095
Author(s):  
Wenzhong Li ◽  
Yu Wang ◽  
Huijing Qi ◽  
Ran Shi ◽  
Jiazhu Li ◽  
...  
Keyword(s):  
Membered Ring ◽  
Cyclization Reaction ◽  
One Pot ◽  
Metal Free ◽  
Cascade Cyclization ◽  
One Pot Synthesis ◽  
Ring Compounds

Metal-free cascade cyclization of 2-acylbenzoic acids with amines provided a one-pot synthesis of diverse isoindoloisoquinoline and benzoindolizinoindole derivatives, which were subsequently used to produce nitrogen-containing nine-membered ring compounds.

Concise asymmetric total synthesis of lycopodine and flabelliformine via cascade cyclization reaction

2019 ◽  
Vol 60 (2) ◽  
pp. 187-190 ◽  
Author(s):  
Kentaro Wada ◽  
Noriyuki Kogure ◽  
Mariko Kitajima ◽  
Hiromitsu Takayama
Keyword(s):  
Total Synthesis ◽  
Cyclization Reaction ◽  
Asymmetric Total Synthesis ◽  
Cascade Cyclization

Synthesis of seco-psymberin/irciniastatin A: the discovery of a novel PhI(OAc)2 mediated cascade cyclization reaction

2008 ◽  
Vol 49 (22) ◽  
pp. 3592-3595 ◽  
Author(s):  
Xianhai Huang ◽  
Ning Shao ◽  
Anandan Palani ◽  
Robert Aslanian ◽  
Alexei Buevich ◽  
...  
Keyword(s):  
Cyclization Reaction ◽  
Cascade Cyclization

A Single-Step Synthesis of Enynes: Pd-Catalyzed Arylalkynylation of Aryl Iodides, Internal Alkynes, and Alkynylsilanes

2010 ◽  
Vol 12 (6) ◽  
pp. 1300-1303 ◽  
Author(s):  
Norio Sakai ◽  
Ryosuke Komatsu ◽  
Naoki Uchida ◽  
Reiko Ikeda ◽  
Takeo Konakahara
Keyword(s):  
Single Step ◽  
Aryl Iodides ◽  
Internal Alkynes
Sign in / Sign up

Export Citation Format

Share Document