An in Silico Investigation of Binding Modes and Pathway of APTO-253 on c-KIT G-Quadruplex DNA

2020 ◽  
Author(s):  
Saikat Pal ◽  
Sandip Paul
Keyword(s):  
Cancer Therapy ◽  
In Silico ◽  
Binding Modes ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
The Stability

The stability of c-KIT G-quadruplex DNA by ligands has been a significant concern in the growing field of cancer therapy. Thus, it is very important to understand the mechanism behind...

Targeting G-quadruplex DNA as Potential Anti-cancer Therapy

2017 ◽  
pp. 129-162
Author(s):  
Riccardo Bonsignore ◽  
Elisa Trippodo ◽  
Giampaolo Barone
Keyword(s):  
Cancer Therapy ◽  
Quadruplex Dna ◽  
Anti Cancer ◽  
G Quadruplex

G-quadruplex DNA/protoporphyrin IX-based synergistic platform for targeted photodynamic cancer therapy

Talanta ◽  
2015 ◽  
Vol 134 ◽  
pp. 298-304 ◽  
Author(s):  
Zhixue Zhou ◽  
Dan Li ◽  
Libing Zhang ◽  
Erkang Wang ◽  
Shaojun Dong
Keyword(s):  
Cancer Therapy ◽  
Protoporphyrin Ix ◽  
Quadruplex Dna ◽  
G Quadruplex ◽  
Photodynamic Cancer Therapy
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