Hypoxia efficient and glutathione-resistant cytoselective ruthenium(ii)-p-cymene-arylimidazophenanthroline complexes: biomolecular interaction and live cell imaging

2020 ◽  
Vol 49 (36) ◽  
pp. 12865-12878 ◽  
Author(s):  
Ashaparna Mondal ◽  
Priyankar Paira

A series of ruthenium(ii)–arene-2-arylimidazophenanthroline based DNA targeting, cytoselective, hypoxia efficient and glutathione-resistant luminescent anticancer drugs have been developed which are also represented as HeLa cell imaging probes.

2019 ◽  
Vol 48 (32) ◽  
pp. 12257-12271 ◽  
Author(s):  
Bidisha Sarkar ◽  
Ashaparna Mondal ◽  
Yukti Madaan ◽  
Nilmadhab Roy ◽  
Anbalagan Moorthy ◽  
...  

The violence of cancer triggered us to design lipophilic, target specific, water soluble, cytoselective and fluorescent Ru(ii)-p-cymene imidazophenanthroline scaffolds as effective DNA targeting agents as well as life cell imaging probes.


2019 ◽  
Vol 55 (6) ◽  
pp. 834-837 ◽  
Author(s):  
Cuiping Guo ◽  
Yu Chang ◽  
Xin Wang ◽  
Chengqian Zhang ◽  
Piliang Hao ◽  
...  

A series of minimalist linkers were developed and have been demonstrated to be suitable for irreversible inhibitors in simultaneous proteome profiling, live-cell imaging and drug screening, thus facilitating the discovery of first-in-class anticancer drugs.


2014 ◽  
Vol 53 (23) ◽  
pp. 5805-5809 ◽  
Author(s):  
Haoxing Wu ◽  
Jun Yang ◽  
Jolita Šečkutė ◽  
Neal K. Devaraj

2019 ◽  
Vol 17 (25) ◽  
pp. 6215-6220 ◽  
Author(s):  
Meng Li ◽  
Ara Lee ◽  
Sungwan Kim ◽  
Annadka Shrinidhi ◽  
Kyeng Min Park ◽  
...  

The potential of cucurbit[7]uril derivatives as live cell imaging probes is demonstrated by investigating the intracellular uptake and excretion of dye-conjugated cucurbit[7]uril derivatives.


2006 ◽  
Vol 13 (6) ◽  
pp. 615-623 ◽  
Author(s):  
Qian Li ◽  
Yunkyung Kim ◽  
Joshua Namm ◽  
Amita Kulkarni ◽  
Gus R. Rosania ◽  
...  

2016 ◽  
Vol 81 (6) ◽  
pp. 2646-2651 ◽  
Author(s):  
Saulo T. A. Passos ◽  
José R. Correa ◽  
Samira L. M. Soares ◽  
Wender A. da Silva ◽  
Brenno A. D. Neto

2020 ◽  
Vol 44 (3) ◽  
pp. 920-931 ◽  
Author(s):  
Santanu Maiti ◽  
Nilmadhab Roy ◽  
Lavanya Thilak Babu ◽  
Prithvi Moharana ◽  
C. C. Athira ◽  
...  

A microwave induced Cu(ii) and Ir(i) catalysed click reaction for the synthesis of anticancer symmetrical and unsymmetrical triazoles.


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