Influence of a 4′-substituent on the efficiency of flavonol-based fluorescent indicators of β-glycosidase activity

2020 ◽  
Vol 18 (38) ◽  
pp. 7635-7648
Author(s):  
Milena Reszka ◽  
Illia E. Serdiuk ◽  
Karol Kozakiewicz ◽  
Andrzej Nowacki ◽  
Henryk Myszka ◽  
...  

Fluorescent probes for glycosidases, based on the excited-state intramolecular proton transfer (ESIPT) phenomenon, are presented.

2018 ◽  
Vol 47 (23) ◽  
pp. 8842-8880 ◽  
Author(s):  
Adam C. Sedgwick ◽  
Luling Wu ◽  
Hai-Hao Han ◽  
Steven D. Bull ◽  
Xiao-Peng He ◽  
...  

We review recent advances in the design and application of excited-state intramolecular proton-transfer (ESIPT) based fluorescent probes. These sensors and imaging agents (probes) are important in biology, physiology, pharmacology, and environmental science.


2021 ◽  
Author(s):  
Narissa Kanlayakan ◽  
Nawee Kungwan

A molecular screening for fluorescent probes harnessing excited-stated intramolecular proton transfer (ESIPT) of NH-type molecules having aminophenyl or tosylaminophenyl as a proton donor and benzimidazole, benzoxazole, benzothiazole, or imidazo[1,2-a]pyridine as...


2019 ◽  
Vol 6 (10) ◽  
pp. 1674-1680 ◽  
Author(s):  
Wei Shi ◽  
Yunfan Yang ◽  
Yu Zhao ◽  
Yongqing Li

Essential comprehension of the ESIPT mechanism in different solvents is helpful to design excellent fluorescent probes for lysosome organelles.


2013 ◽  
Vol 85 (7) ◽  
pp. 1465-1478 ◽  
Author(s):  
Guoqiang Yang ◽  
Shayu Li ◽  
Shuangqing Wang ◽  
Rui Hu ◽  
Jiao Feng ◽  
...  

Excited-state intramolecular proton-transfer (ESIPT) compounds and intramolecular charge-transfer (ICT) compounds have attracted attention due to their interesting and even unique emission properties. The intense and environment-sensitive emission showed by some members of the two families has been exploited in fluorescent probes for various forms of environmental sensing. In this paper, we summarize our recent study on the utilization of novel ESIPT and ICT compounds with intense emission as fluorescent probes after an introduction to the ESIPT and/or ICT processes and related photophysics mechanism.


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