Copper and manganese co-mediated cascade aza-Michael addition/cyclization and azidation of 1,3-enynes: regioselective synthesis of fully substituted azido pyrroles

2020 ◽  
Vol 18 (43) ◽  
pp. 8908-8915
Author(s):  
Junying Ge ◽  
Qiuping Ding ◽  
Man Yang ◽  
Tian He ◽  
Yiyuan Peng
Keyword(s):  
Michael Addition ◽  
Oxidative Cyclization ◽  
Regioselective Synthesis ◽  
Trimethylsilyl Azide

A Cu and Mn co-mediated aerobic oxidative cyclization and azidation reaction of 1,3-enynes with amines and trimethylsilyl azide has been developed to synthesize fully substituted azido pyrroles.

Highly efficient regioselective synthesis of pyrroles via a tandem enamine formation–Michael addition–cyclization sequence under catalyst- and solvent-free conditions

2015 ◽  
Vol 17 (6) ◽  
pp. 3415-3423 ◽  
Author(s):  
Thavaraj Vivekanand ◽  
Perumal Vinoth ◽  
B. Agieshkumar ◽  
Natarajan Sampath ◽  
Arumugam Sudalai ◽  
...  
Keyword(s):  
Column Chromatography ◽  
Michael Addition ◽  
Solvent Free ◽  
Regioselective Synthesis ◽  
Highly Efficient ◽  
Solvent Free Conditions ◽  
Enamine Formation

An efficient three-component, catalyst-, solvent-, and column chromatography-free procedure was developed for the synthesis of 3-(1H-pyrrol-3-yl)indolin-2-ones.

NHC-catalyzed oxidative cyclization reaction for the synthesis of 3-substituted phthalides

2014 ◽  
Vol 12 (15) ◽  
pp. 2388-2393 ◽  
Author(s):  
So Won Youn ◽  
Hyoung Sub Song ◽  
Jong Hyub Park
Keyword(s):  
Michael Addition ◽  
Functional Group ◽  
Addition Reaction ◽  
Oxidative Cyclization ◽  
Cyclization Reaction ◽  
Michael Addition Reaction ◽  
Stereogenic Center

An efficient NHC-catalyzed domino oxidation/oxa-Michael addition reaction of 2-alkenylbenzaldehydes has been developed to afford 3-substituted phthalides bearing a C3-stereogenic center with a broad substrate scope and wide functional group tolerance.

Nano-NiFe2O4 catalyzed microwave assisted one-pot regioselective synthesis of novel 2-alkoxyimidazo[1,2-a]pyridines under aerobic conditions

RSC Advances ◽  
2016 ◽  
Vol 6 (15) ◽  
pp. 12402-12407 ◽  
Author(s):  
Soumen Payra ◽  
Arijit Saha ◽  
Subhash Banerjee
Keyword(s):  
Michael Addition ◽  
Regioselective Synthesis ◽  
Reusable Catalyst ◽  
One Pot ◽  
Aerobic Conditions ◽  
Microwave Assisted ◽  
Ligand Transfer

Here, we have demonstrated regioselective synthesis of novel 2-alkoxy-3-arylimidazo[1,2-a]pyridines using nano-NiFe2O4 as reusable catalyst via one-pot sequential aza-Michael addition, Fe-promoted ligand transfer and C–H imination reactions.

Silver-Promoted Oxidative Cyclization of 1,6-Enynes: Highly Regioselective Synthesis of Phosphorated Fluorene Derivatives

2014 ◽  
Vol 16 (21) ◽  
pp. 5616-5619 ◽  
Author(s):  
Zhao-Zhao Zhou ◽  
Dong-Po Jin ◽  
Lian-Hua Li ◽  
Yu-Tao He ◽  
Ping-Xin Zhou ◽  
...  
Keyword(s):  
Oxidative Cyclization ◽  
Regioselective Synthesis

ChemInform Abstract: Precursor Directed Regioselective Synthesis of Partially Reduced Benzo[e]indene Through Oxidative Cyclization and Benzo[h]quinolines.

ChemInform ◽  
2015 ◽  
Vol 46 (28) ◽  
pp. no-no
Author(s):  
Surjeet Singh ◽  
Rahul Panwar ◽  
Pratik Yadav ◽  
Ismail Althagafi ◽  
Satya Narayan Sahu ◽  
...  
Keyword(s):  
Oxidative Cyclization ◽  
Regioselective Synthesis
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