Enzyme-free dual-amplification strategy for the rapid, single-step detection of nucleic acids based on hybridization chain reaction initiated entropy-driven circuit reaction

2018 ◽  
Vol 273 ◽  
pp. 393-399 ◽  
Author(s):  
Dongmei Huang ◽  
Xinmin Li ◽  
Bo Shen ◽  
Jia Li ◽  
Xiaojuan Ding ◽  
...  
Keyword(s):  
Nucleic Acids ◽  
Single Step ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Step Detection ◽  
Dual Amplification ◽  
Amplification Strategy

Target-directed enzyme-free dual-amplification DNA circuit for rapid signal amplification

2020 ◽  
Vol 8 (47) ◽  
pp. 10770-10775
Author(s):  
Chao Xing ◽  
Ziyi Chen ◽  
Cheng Zhang ◽  
Jun Wang ◽  
Chunhua Lu
Keyword(s):  
Nucleic Acids ◽  
Small Molecules ◽  
Signal Amplification ◽  
Fluorescence Analysis ◽  
Single Step ◽  
Hybridization Chain Reaction ◽  
Chain Reaction ◽  
Dual Amplification

An enzyme-free, single-step and rapid signal amplification DNA circuit was developed by integrating target-directed entropy-driven catalysis and hybridization chain reaction for fluorescence analysis of nucleic acids and small molecules.

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