Design and evaluation of IKK-activated GSK3 inhibitory peptide as an inflammation-responsive anti-colitic therapeutics

2021 ◽  
Author(s):  
Sungchae Hong ◽  
Sanghyun Ju ◽  
Jin-Wook Yoo ◽  
Nam-Chul Ha ◽  
Yunjin Jung
Keyword(s):  
Therapeutic Target ◽  
Glycogen Synthase ◽  
Glycogen Synthase Kinase ◽  
Glycogen Synthase Kinase 3Β ◽  
Inhibitory Peptide ◽  
Promising Therapeutic Target

Glycogen synthase kinase-3β (GSK3β), a multi-functional kinase, is a promising therapeutic target for the treatment of inflammation. Inhibitory B kinase (IKK)-activated GSK3β inhibitory peptide (IAGIP) was designed as an inflammation-responsive...

scholarly journals Glycogen synthase kinase 3β as a potential therapeutic target in synovial sarcoma and fibrosarcoma

2019 ◽  
Vol 111 (2) ◽  
pp. 429-440 ◽  
Author(s):  
Kensaku Abe ◽  
Norio Yamamoto ◽  
Takahiro Domoto ◽  
Dilireba Bolidong ◽  
Katsuhiro Hayashi ◽  
...  
Keyword(s):  
Synovial Sarcoma ◽  
Therapeutic Target ◽  
Glycogen Synthase ◽  
Glycogen Synthase Kinase ◽  
Glycogen Synthase Kinase 3Β ◽  
Potential Therapeutic Target

Glycogen Synthase Kinase-3β as a Putative Therapeutic Target for Bipolar Disorder

2018 ◽  
Vol 19 (8) ◽  
pp. 663-673 ◽  
Author(s):  
Manoj P. Dandekar ◽  
Samira S. Valvassori ◽  
Gustavo C. Dal-Pont ◽  
Joao Quevedo
Keyword(s):  
Bipolar Disorder ◽  
Therapeutic Target ◽  
Glycogen Synthase ◽  
Glycogen Synthase Kinase ◽  
Glycogen Synthase Kinase 3Β

Is Going for Cure in CML Targeting Aberrant Glycogen Synthase Kinase 3β?

2017 ◽  
Vol 18 (4) ◽  
pp. 396-404
Author(s):  
Concetta Saponaro ◽  
Michele Maffia ◽  
Nicola Renzo ◽  
Addolorata Coluccia
Keyword(s):  
Glycogen Synthase ◽  
Glycogen Synthase Kinase ◽  
Glycogen Synthase Kinase 3Β
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