Convergent chemoenzymatic synthesis and biological evaluation of a heparan sulfate proteoglycan syndecan-1 mimetic

2021 ◽  
Vol 57 (27) ◽  
pp. 3407-3410
Author(s):  
Jia Gao ◽  
Yongmei Xu ◽  
Jian Liu ◽  
Xuefei Huang
Keyword(s):  
Heparan Sulfate ◽  
Biological Evaluation ◽  
Heparan Sulfate Proteoglycan ◽  
Chemoenzymatic Synthesis ◽  
Sulfate Proteoglycan ◽  
Biological Studies ◽  
Synthesis Strategy ◽  
Synthesis And Biological Evaluation

A new convergent chemoenzymatic synthesis strategy has been established to efficiently synthesize a mimetic of structurally well-defined heparan sulfate proteoglycan syndecan-1 glyco-polypeptide at a milligram scale to enable biological studies.

Alterations in the basement membrane (heparan sulfate) proteoglycan in diabetic mice

Diabetes ◽  
1982 ◽  
Vol 31 (2) ◽  
pp. 185-188 ◽  
Author(s):  
D. H. Rohrbach ◽  
J. R. Hassell ◽  
H. K. Kleinman ◽  
G. R. Martin
Keyword(s):  
Basement Membrane ◽  
Heparan Sulfate ◽  
Heparan Sulfate Proteoglycan ◽  
Sulfate Proteoglycan ◽  
Diabetic Mice

Targeting Mechanism of a Novel Liver-targeting Interferon IFN-CSP Involves Liver Heparan Sulfate Proteoglycan

2016 ◽  
Vol 13 (4) ◽  
pp. 528-533 ◽  
Author(s):  
Xuemei Lu ◽  
Jie Wang ◽  
Xiaobao Jin ◽  
Yanting Huang ◽  
Wenting Zeng ◽  
...  
Keyword(s):  
Heparan Sulfate ◽  
Heparan Sulfate Proteoglycan ◽  
Sulfate Proteoglycan ◽  
Liver Targeting

Immunohistochemical Study of Heparan Sulfate Proteoglycan in Adenocarcinomas of the Pancreas

Pancreas ◽  
1994 ◽  
Vol 9 (6) ◽  
pp. 758-763 ◽  
Author(s):  
Zhao-hui Wang ◽  
Tadao Manabe ◽  
Gakuji Ohshio ◽  
Takashi Imamura ◽  
Tsunehiro Yoshimura ◽  
...  
Keyword(s):  
Heparan Sulfate ◽  
Immunohistochemical Study ◽  
Heparan Sulfate Proteoglycan ◽  
Sulfate Proteoglycan

scholarly journals Fatty acylation of heparan sulfate proteoglycan from human colon carcinoma cells.

1990 ◽  
Vol 265 (32) ◽  
pp. 19980-19989
Author(s):  
R V Iozzo ◽  
I Kovalszky ◽  
N Hacobian ◽  
P K Schick ◽  
J S Ellingson ◽  
...  
Keyword(s):  
Heparan Sulfate ◽  
Colon Carcinoma ◽  
Human Colon ◽  
Heparan Sulfate Proteoglycan ◽  
Carcinoma Cells ◽  
Sulfate Proteoglycan ◽  
Fatty Acylation ◽  
Colon Carcinoma Cells ◽  
Human Colon Carcinoma

scholarly journals Identification of cDNA clones encoding different domains of the basement membrane heparan sulfate proteoglycan.

1988 ◽  
Vol 263 (31) ◽  
pp. 16379-16387 ◽  
Author(s):  
D M Noonan ◽  
E A Horigan ◽  
S R Ledbetter ◽  
G Vogeli ◽  
M Sasaki ◽  
...  
Keyword(s):  
Basement Membrane ◽  
Heparan Sulfate ◽  
Heparan Sulfate Proteoglycan ◽  
Cdna Clones ◽  
Sulfate Proteoglycan
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