Impact of Licochalcone A on the Progression of Diabetic Nephropathy in Type 2 Diabetes Mellitus of C57BL/6 Mice

Food & Function ◽

10.1039/d1fo01630j ◽

2021 ◽

Author(s):

Zhonghua Luo ◽

Tao Li ◽

Qingqing Gao ◽

Yu Chen ◽

Guangyue Su ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Diabetic Nephropathy ◽

Microvascular Complication ◽

Licochalcone A

Diabetic nephropathy (DN) is the most common chronic microvascular complication of diabetes. Therefore, it is of great significance to effectively prevent and treat DN. Licochalcone A (LicA) is a flavonoid...

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Level of hydrogen sulfide in patients with type 2 diabetes mellitus depending on the presence of diabetic nephropathy

Acta Medica Leopoliensia ◽

10.25040/aml2017.04.012 ◽

2017 ◽

Vol 23 (4) ◽

pp. 12-14

Author(s):

D.Yu. Kutsyk ◽

◽

Ye.Ya. Sklyarov ◽

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Diabetic Nephropathy ◽

Hydrogen Sulfide

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Faculty Opinions recommendation of A randomized controlled study of finerenone versus placebo in Japanese patients with type 2 diabetes mellitus and diabetic nephropathy.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727146123.793527044 ◽

2017 ◽

Author(s):

Luis Ruilope ◽

Enrique Morales

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Diabetic Nephropathy ◽

Japanese Patients ◽

Randomized Controlled Study ◽

Controlled Study ◽

Randomized Controlled

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PGNMID in a patient with diabetes mellitus

Journal of Onco-Nephrology ◽

10.1177/2399369320984782 ◽

2021 ◽

pp. 239936932098478

Author(s):

Joana Marques ◽

Patrícia Cotovio ◽

Mário Góis ◽

Helena Sousa ◽

Fernando Nolasco

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Diabetic Nephropathy ◽

Renal Disease ◽

Renal Involvement ◽

Organ Damage ◽

Therapeutic Implications ◽

Stage Renal Disease

Diabetic nephropathy is a well known complication of diabetes mellitus and the leader cause of end -stage renal disease worldwide. Nonetheless, other forms of renal involvement can occur in diabetic population. Since it has prognostic and therapeutic implications, differentiating non-diabetic renal disease from diabetic nephropathy is of great importance. We report an 80-year-old man with well-controlled type 2 diabetes mellitus and hypertension, who presented with rapid deterioration of renal function, nephrotic proteinuria, microscopic hematuria and leukocyturia. The atypical clinical presentation prompted us to perform a kidney biopsy. A diagnosis of proliferative glomerulonephritis with monoclonal immunoglobulin deposits (light chain only variant) was made, with however some chronic histological aspects which made us took a conservative therapeutic attitude. We emphasize that other causes of chronic proteinuric kidney disease should be considered in patients with type 2 diabetes mellitus, based on clinical suspicion, absence of other organ damage and mostly if an atypical presentation is seen. We review the spectrum of monoclonal gammopathies of renal significance, focusing on this rare and newly describe entity.

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