scholarly journals Magnetic sulfonated polysaccharides as efficient catalysts for synthesis of isoxazole-5-one derivatives possessing a substituted pyrrole ring, as anti-cancer agents

RSC Advances ◽  
2021 ◽  
Vol 11 (58) ◽  
pp. 36958-36964
Author(s):  
Zarrin Ghasemi ◽  
Afsaneh Hamidian Amale ◽  
Sajjad Azizi ◽  
Sepideh Valizadeh ◽  
Jafar Soleymani
Keyword(s):  
Pyrrole Ring ◽  
Anti Cancer

Four magnetic polysaccharides containing acidic groups were used as catalysts for the synthesis of 4-(2-pyrrolyl) methylene-isoxazole-5-ones. The products showed anti-cancer activities.

Indole: A Privileged Heterocyclic Moiety in the Management of Cancer

2021 ◽  
Vol 25 ◽  
Author(s):  
Reyaz Hassan Mir ◽  
Roohi Mohi-ud-din ◽  
Taha Umair Wani ◽  
Mohammad Ovais Dar ◽  
Abdul Jaleel Shah ◽  
...  
Keyword(s):  
Benzene Ring ◽  
Pyrrole Ring ◽  
Synthetic Chemistry ◽  
Pharmacological Profile ◽  
Dna Topoisomerases ◽  
Pim Kinases ◽  
Current Review ◽  
Bicyclic Structure ◽  
Anti Cancer ◽  
Heterocyclic Moiety

: Heterocyclic are a class of compounds that are intricately entwined into life processes. Almost more than 90% of marketed drugs carry heterocycles. Synthetic chemistry, in turn, allocates a cornucopia of heterocycles. Among the heterocycles, indole, a bicyclic structure consisting of a six-membered benzene ring fused to a five-membered pyrrole ring with numerous pharmacophores that generate a library of various lead molecules. Due to its profound pharmacological profile, indole got wider attention around the globe to explore it fully in the interest of mankind. The current review covers recent advancements on indole in the design of various anti-cancer agents acting by targeting various enzymes or receptors, including (HDACs), sirtuins, PIM kinases, DNA topoisomerases, and σ receptors.

Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes

Xenobiotica ◽  
2009 ◽  
Vol 00 (00) ◽  
pp. 090901052053001-8
Author(s):  
K. Murai ◽  
H. Yamazaki ◽  
K. Nakagawa ◽  
R. Kawai ◽  
T. Kamataki
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cancer Drug ◽  
Anti Cancer ◽  
Cytochrome P450 2A6

Psychogenic Mass Syndrome in Anti-Cancer Drug Exposure

2010 ◽  
Author(s):  
N. Magnavita ◽  
I. lavicoli ◽  
V. Leso ◽  
A. Bergamaschi
Keyword(s):  
Drug Exposure ◽  
Cancer Drug ◽  
Anti Cancer

Tulbaghia alliacea: A potential anti-cancer phytotherapy

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
S Thamburan ◽  
F February ◽  
M Meyer ◽  
J Rees ◽  
Q Johnson
Keyword(s):  
Anti Cancer

Anti-cancer thymoquinone from Nigella sativa

Planta Medica ◽  
2013 ◽  
Vol 79 (13) ◽  
Author(s):  
WW Li ◽  
JO Rosa ◽  
MR Siddique ◽  
B Bajana ◽  
J Sulé-Suso ◽  
...  
Keyword(s):  
Nigella Sativa ◽  
Anti Cancer

Benzoxazinoids in human diet: an anti-cancer agent?

2019 ◽  
Author(s):  
B Bhattarai ◽  
SK Steffensen ◽  
PL Gregersen ◽  
JH Jensen ◽  
KD Sørensen ◽  
...  
Keyword(s):  
Human Diet ◽  
Anti Cancer ◽  
Cancer Agent

Audit of a new nurse-led non-medical prescribing (NMP) clinic for systemic anti-cancer agents (SACTs)

2017 ◽  
Author(s):  
Philippa Davies ◽  
Elizabeth Quaglia ◽  
Aisling McSweeney ◽  
Martyn Caplin ◽  
Christina Thirlwell
Keyword(s):  
Anti Cancer
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