scholarly journals Synthesis and biological evaluation of new derivatives of thieno-thiazole and dihydrothiazolo-thiazole scaffolds integrated with a pyrazoline nucleus as anticancer and multi-targeting kinase inhibitors

RSC Advances ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 561-577
Author(s):  
Ismail M. M. Othman ◽  
Zahra M. Alamshany ◽  
Nada Y. Tashkandi ◽  
Mohamed A. M. Gad-Elkareem ◽  
Somaia S. Abd El-Karim ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Protein Kinases ◽  
Kinase Inhibitors ◽  
Biological Evaluation ◽  
Cancer Development ◽  
Kinase Family ◽  
Synthesis And Biological Evaluation ◽  
Derivatives Of

Deregulation of various protein kinases is considered as one of the important factors resulting in cancer development and metastasis, thus multi-targeting the kinase family is one of the most important strategies in current cancer therapy.

scholarly journals Synthesis and Biological Evaluation of RGD-Conjugated MEK1/2 Kinase Inhibitors for Integrin-Targeted Cancer Therapy

Molecules ◽  
2013 ◽  
Vol 18 (11) ◽  
pp. 13957-13978 ◽  
Author(s):  
Xiaoxiao Li ◽  
Jianjun Hou ◽  
Chao Wang ◽  
Xinjie Liu ◽  
Hongyan He ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Kinase Inhibitors ◽  
Biological Evaluation ◽  
Targeted Cancer Therapy ◽  
Synthesis And Biological Evaluation

Design, Synthesis and Biological Evaluation of Novel Aminosaccharide Derivatives of Combretastatin A-4

2013 ◽  
Vol 10 (10) ◽  
pp. 935-941
Author(s):  
Yan Tang ◽  
Zhewei Tu ◽  
Jing Sun ◽  
Xiong Zhu ◽  
Kun Liu ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation ◽  
Derivatives Of

Synthesis and biological evaluation of seliciclib derivatives as potent and selective CDK9 inhibitors for prostate cancer therapy

2021 ◽  
Vol 152 (1) ◽  
pp. 109-120
Author(s):  
Aisha A. Alsfouk ◽  
Hanan M. Alshibl ◽  
Najla A. Altwaijry ◽  
Bshra A. Alsfouk ◽  
Ebtehal S. Al-Abdullah
Keyword(s):  
Prostate Cancer ◽  
Cancer Therapy ◽  
Biological Evaluation ◽  
Prostate Cancer Therapy ◽  
Synthesis And Biological Evaluation

ChemInform Abstract: Synthesis and Preliminary Biological Evaluation of New Derivatives of the Marine Alkaloid Leucettamine B as Kinase Inhibitors.

ChemInform ◽  
2010 ◽  
Vol 41 (23) ◽  
pp. no-no
Author(s):  
Mansour Debdab ◽  
Steven Renault ◽  
Olivier Lozach ◽  
Laurent Meijer ◽  
Ludovic Paquin ◽  
...  
Keyword(s):  
Kinase Inhibitors ◽  
Biological Evaluation ◽  
Marine Alkaloid ◽  
Derivatives Of

Synthesis, characterization and in vitro and in vivo anticancer activity of Pt(iv) derivatives of [Pt(1S,2S-DACH)(5,6-dimethyl-1,10-phenanthroline)]

2017 ◽  
Vol 46 (21) ◽  
pp. 7005-7019 ◽  
Author(s):  
Benjamin W. J. Harper ◽  
Emanuele Petruzzella ◽  
Roman Sirota ◽  
Fernanda Fabiola Faccioli ◽  
Janice R. Aldrich-Wright ◽  
...  
Keyword(s):  
Anticancer Activity ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation ◽  
Derivatives Of

Synthesis and biological evaluation in vitro and in vivo of functionalized Pt(iv) derivatives of Pt56MeSS.

Asymmetric Synthesis and Biological Evaluation of Glycosidic Prodrugs for a Selective Cancer Therapy

ChemMedChem ◽  
2008 ◽  
Vol 3 (12) ◽  
pp. 1946-1955 ◽  
Author(s):  
Lutz F. Tietze ◽  
J. Marian von Hof ◽  
Birgit Krewer ◽  
Michael Müller ◽  
Felix Major ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Asymmetric Synthesis ◽  
Biological Evaluation ◽  
Synthesis And Biological Evaluation

Design, Synthesis, and Biological Evaluation of Novel Fluoro Derivatives of BCNA

2009 ◽  
Vol 82 (2) ◽  
pp. A57
Author(s):  
Marco Derudas ◽  
Maurizio Quintiliani ◽  
Christopher McGuigan ◽  
Andrea Brancale ◽  
Geoffrey Henson ◽  
...  
Keyword(s):  
Biological Evaluation ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation ◽  
Derivatives Of ◽  
Fluoro Derivatives
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