Insights into Cascade and Sequential one pot pathways for reductive amination of aldehydes paired with bio-derived levulinic acid to N-substituted pyrrolidones using molecular hydrogen

Reaction Chemistry & Engineering ◽

10.1039/d1re00384d ◽

2022 ◽

Author(s):

Tejas A Gokhale ◽

Amol Bhanudas Raut ◽

Sheetal K Chawla ◽

Bhalchandra Mahadeo Bhanage

Keyword(s):

Molecular Hydrogen ◽

Levulinic Acid ◽

Reductive Amination ◽

One Pot ◽

Aryl Aldehydes

This work aims to explore cascade and sequential one pot syntheses pathways for N-substituted pyrrolidones from aryl aldehydes and bio-derived levulinic acid (LA) using molecular hydrogen and ammonia. This process...

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Reductive amination of levulinic acid or its derivatives to pyrrolidones over heterogeneous catalysts in the batch and continuous flow reactors: A review

Renewable and Sustainable Energy Reviews ◽

10.1016/j.rser.2021.110876 ◽

2021 ◽

Vol 143 ◽

pp. 110876

Author(s):

M.V. Bukhtiyarova ◽

G.A. Bukhtiyarova

Keyword(s):

Continuous Flow ◽

Levulinic Acid ◽

Heterogeneous Catalysts ◽

Reductive Amination ◽

Flow Reactors ◽

Continuous Flow Reactors

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Mild reduction with silanes and reductive amination of levulinic acid using a simple manganese catalyst

Inorganica Chimica Acta ◽

10.1016/j.ica.2020.120167 ◽

2021 ◽

Vol 516 ◽

pp. 120167

Author(s):

Diego A. Roa ◽

Juventino J. Garcia

Keyword(s):

Levulinic Acid ◽

Reductive Amination ◽

Mild Reduction

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Cobalt encapsulated in N‑doped graphene sheet for one-pot reductive amination to synthesize secondary amines

Molecular Catalysis ◽

10.1016/j.mcat.2021.111504 ◽

2021 ◽

Vol 505 ◽

pp. 111504

Author(s):

Lin Liu ◽

Wenxiu Li ◽

Ran Qi ◽

Qingqing Zhu ◽

Jing Li ◽

...

Keyword(s):

Graphene Sheet ◽

Reductive Amination ◽

Secondary Amines ◽

One Pot ◽

Doped Graphene

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Selectively Reductive Amination of Levulinic Acid with Aryl amines to N-substituted Aryl Pyrroles

Green Energy & Environment ◽

10.1016/j.gee.2021.04.010 ◽

2021 ◽

Author(s):

Cailing Wu ◽

Mengjie Lou ◽

Mingming Sun ◽

Huiyong Wang ◽

Zhiyong Li ◽

...

Keyword(s):

Levulinic Acid ◽

Reductive Amination ◽

Aryl Amines

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Facile Synthesis of COF-Supported Reduced Pd-Based Catalyst for One-Pot Reductive Amination of Aldehydes

Catalysts ◽

10.3390/catal11020287 ◽

2021 ◽

Vol 11 (2) ◽

pp. 287

Author(s):

Jianguo Liu ◽

Mingyue Zhang ◽

Longlong Ma

Keyword(s):

Heterogeneous Catalysts ◽

Reductive Amination ◽

Secondary Amines ◽

Metallic State ◽

One Pot ◽

Effective Synthesis ◽

Pharmaceutical Industries ◽

The One ◽

Heterocyclic Aldehydes ◽

Supported Pd

Dibenzylamine motifs are an important class of crucial organic compounds and are widely used in fine chemical and pharmaceutical industries. The development of the efficient, economical, and environmentally friendly synthesis of amines using transition metal-based heterogeneous catalysts remains both desirable and challenging. Herein, we prepared the covalent organic framework (COF)-supported heterogeneous reduced COF-supported Pd-based catalyst and used it for the one-pot reductive amination of aldehydes. There are both Pd metallic state and oxidated Pdσ+ in the catalysts. Furthermore, in the presence of the reduced COF-supported Pd-based catalyst, many aromatic, aliphatic, and heterocyclic aldehydes with various functional groups substituted were converted to their corresponding amines products in good to excellent selectivity (up to 91%) under mild reaction conditions (70 °C, 2 h, NH3, 20 bar H2). This work expands the covalent organic frameworks for the material family and its support catalyst, opening up new catalytic applications in the economical, practical, and effective synthesis of secondary amines.

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