Manganese (I)-Catalyzed Access to 1,2-Bisphosphine Ligands

Chiral bisphosphine ligands are of key importance in transition-metal-catalyzed asymmetric synthesis of optically active products. However, the transition metals typically used are scarce and expensive noble metals, while the synthetic routes...

ChemInform Abstract: TRANSITION METAL CATALYZED ASYMMETRIC ORGANIC SYNTHESES VIA POLYMER-ATTACHED OPTICALLY ACTIVE PHOSPHINE LIGANDS. SYNTHESIS OF R AMINO ACIDS AND HYDRATROPIC ACID BY HYDROGENATION

Chemischer Informationsdienst ◽

10.1002/chin.197818313 ◽

1978 ◽

Vol 9 (18) ◽

Author(s):

N. TAKAISHI ◽

H. IMAI ◽

C. A. BERTELO ◽

J. K. STILLE

Keyword(s):

Amino Acids ◽

Transition Metal ◽

Optically Active ◽

Phosphine Ligands ◽

Organic Syntheses ◽

Asymmetric synthesis to chiral organosilicon compounds via transition metal-catalyzed stereoselective C-H activation and silylation

Chemical Communications ◽

10.1039/d1cc02839a ◽

2021 ◽

Author(s):

Ming Zhang ◽

Shan Gao ◽

Juan Tang ◽

Ling Chen ◽

Aihua Liu ◽

...

Keyword(s):

Transition Metal ◽

Asymmetric Synthesis ◽

Organosilicon Compounds ◽

Feature Article ◽

This feature article introduces the progress of transition metal-catalyzed stereoselective sp2 and sp3 C-H activation and silylation to synthesize chiral organosilicon compounds, the asymmetric C-H silylation includes intramolecular cyclizing silylation...

Transition metal-catalyzed synthesis of spirooxindoles

RSC Advances ◽

10.1039/d1ra00139f ◽

2021 ◽

Vol 11 (13) ◽

pp. 7146-7179

Author(s):

P. V. Saranya ◽

Mohan Neetha ◽

Thaipparambil Aneeja ◽

Gopinathan Anilkumar

Keyword(s):

Transition Metal ◽

Transition Metals ◽

Antimicrobial Agents ◽

Recent Advances ◽

Spirooxindoles are used as anticancer-, antiviral-, antimicrobial agents etc. The use of transition metals as catalysts for the synthesis of spirooxindoles is advancing rapidly. Here, we focus on recent advances in transition metal-catalyzed synthesis of spirooxindoles.

Amide-Directed Reactions of Small Carbocycles

Current Organic Chemistry ◽

10.2174/1385272825666210706124215 ◽

2021 ◽

Vol 25 ◽

Author(s):

Pavel M. Yamanushkin ◽

Marina Rubina ◽

Michael Rubin

Keyword(s):

Transition Metal ◽

Transition Metals ◽

Nucleophilic Addition ◽

Addition Reactions ◽

: The topic of this review is the amide-directed functionalization of strained carbocycles — specifically, unsaturated or saturated three- and four-membered rings. The following approaches are discussed: a) directed carbometallation and hydrometallation of cyclopropenes catalyzed by transition metals; b) directed metal-templated nucleophilic addition reactions; c) directed C-H functionalization, including transition metal-catalyzed C-H-activation reactions; and d) directed radical additions.

ChemInform Abstract: 2,2′-Dimethyl-6,6′-bis(diphenylphosphino)biphenyl (BIPHEMP) as a Chiral Ligand for Transition Metal Catalyzed Asymmetric Synthesis of Binaphthyls and for Asymmetric Hydrogenation. A Comparison with BINAP.

ChemInform ◽

10.1002/chin.198946162 ◽

1989 ◽

Vol 20 (46) ◽

Author(s):

T. FREJD ◽

T. KLINGSTEDT

Keyword(s):

Transition Metal ◽

Asymmetric Synthesis ◽

Asymmetric Hydrogenation ◽

Chiral Ligand ◽

Directing-Group-Assisted Transition-Metal-Catalyzed Direct C–H Oxidative Annulation of Arenes with Alkynes for Facile Construction of Various Oxygen Heterocycles

Synthesis ◽

10.1055/s-0039-1690816 ◽

2020 ◽

Vol 52 (07) ◽

pp. 993-1006 ◽

Cited By ~ 3

Author(s):

Guanghua Kuang ◽

Guangyuan Liu ◽

Xingxing Zhang ◽

Naihao Lu ◽

Yiyuan Peng ◽

...

Keyword(s):

Transition Metal ◽

Noble Metals ◽

Metal Catalysts ◽

Transition Metal Catalysts ◽

Research Papers ◽

Recent Advances ◽

Oxygen Heterocycles ◽

Directing Group ◽

The most recent advances in the construction of oxygen heterocycles by the directing-group-assisted transition-metal-catalyzed direct oxidative annulation of arenes with diverse alkynes are summarized in this review. More than 140 recent research papers and many closely related reviews are referenced in this paper. Nine different oxygen heterocycles frameworks are discussed. Several traditional transition-metal catalysts as well as some classical non-noble metals are utilized to promote the annulation. Three plausible controlling models are disclosed to clarify the excellent regioselectivity outcomes achieved in case of unsymmetrical alkyne substrates.1 Introduction2 Coumarins3 I socoumarins and Their Analogues4 2-Pyrones and Their Analogues5 Chromones and Chroman-4-ones6 Chromenes and Isochromenes7 Fused Polycyclic Oxygen Heteroaromatics8 Benzofurans, Dihydrobenzofurans, and Furans9 Phthalides and Benzofuranones10 Benzoxepines11 Conclusion

Asymmetric synthesis: From transition metals to organocatalysis

Pure and Applied Chemistry ◽

10.1351/pac200880050953 ◽

2008 ◽

Vol 80 (5) ◽

pp. 953-966 ◽

Cited By ~ 22

Author(s):

Pavel Kočovský ◽

Andrei V. Malkov

Keyword(s):

Transition Metal ◽

Transition Metals ◽

Asymmetric Synthesis ◽

Absolute Configuration ◽

Nucleoside Analogs ◽

Oxide Catalysts ◽

Lewis Base ◽

New Approach ◽

Π Interactions ◽

Umpolung in the allylation reaction is discussed with examples drawn from transition-metal-catalyzed allylic substitution (with the allylic unit acting as an electrophile) and Lewis base-catalyzed allylation of aldehydes with allyltrichlorosilane (with the allyl acting as a nucleophile). Iridium-catalyzed electrophilic allylation of O-nucleophiles has been employed in our new approach to C-nucleoside analogs, where the C-O bond (rather than C-C) was constructed stereospecifically. Variation of the absolute configuration in the starting segments allowed the synthesis of all four combinations of D/L-α/β-ribosides. In the nucleophilic allylation of aldehydes, chiral pyridine-type N-oxide catalysts are presented, in particular QUINOX and METHOX, and the intriguing behavior of QUINOX is discussed. Here, the π-π interactions between the substrate aldehyde and the catalyst are suggested to rationalize the experimental observations. Good correlation between the calculated energies for the transition states and the experimentally observed enantioselectivities has been obtained.