Increased Donnan Exclusion at High Salt Concentrations

Soft Matter ◽  
2022 ◽  
Author(s):  
Kevin W Gao ◽  
Xiaopeng Yu ◽  
Robert M. Darling ◽  
John Newman ◽  
Nitash P Balsara

The swelling of univalent and multivalent charged polymeric networks in electrolytic solutions is studied using a classical thermodynamic model. Such systems were first modeled by Donnan, who derived an expression...

2016 ◽  
Vol 138 (10) ◽  
Author(s):  
Leonardo S. de B. Alves

An approximate solution of the classical thermodynamic model for compressible heat transfer of a quiescent supercritical fluid under microgravity leads to the well-known piston effect relaxation time tPE=tD/(γ0−1)2, where tD is the thermal diffusion relaxation time and γ0 is the ratio between specific heats. This relaxation time represents an upper bound for the asymptotic bulk temperature behavior during very early times, which shows a strong algebraic relaxation due to the piston effect. This paper demonstrates that an additional relaxation time associated with the piston effect exists in this classical thermodynamic model, namely, tE=tD/γ0. Furthermore, it shows that tE represents the time required by the bulk temperature to reach steady-state. Comparisons with a numerical solution of the compressible Navier–Stokes equations as well as experimental data indicate the validity of this new analytical expression and its physical interpretation.


1995 ◽  
Vol 5 (10) ◽  
pp. 1241-1246 ◽  
Author(s):  
Thomas A. Vilgis ◽  
Michael P. Solf

1979 ◽  
Author(s):  
H. P. Muller ◽  
N. H. van Tilburg ◽  
R. M. Bertina ◽  
J. J. Veltkamp

FVIII was separated into low molecular weight FVIII (LMW FVIII) and high molecular weight FVIII (HMW FVIII) by gel chromatography in the presence of high salt concentration or by high salt elution of LMW FVIII from FVIII bound to anti HMW FVII-Sepharose. Specific antibodies were raised in rabbits against HMW FVIII and LMW FVIII. After removal of the contaminating anti HMW activities the rabbit anti LMW FVIII was still able to neutralize the FVIII coagulant activity of normal plasma and of IMW FVIII with canparable efficiency and it had no effect on the VIIIR:WF of FVIII in normal plasma or in HMW FVIII. Anti LMW FVIII does not bind to HMW FVIII and does not precipitate FVIII as tested by counter immunoelectrophoresis. Rabbit anti HMW FVIII precipitates FVIII in normal plasma, inhibits VIIIR:WF activity, while it has no effect on the FVIII coagulant activity of LMW FVIII. The coagulant activity of FVIII in normal plasma is slightly inhibited by anti HMW FVIII presumably by non-specific effects (sterical hindrance). It is concluded that inhibitory antibodies against VIII:C raised in rabbits recognize antigenic structures only present on LMW FVIII. Antibodies against HMW FVIII raised in rabbits appears to recognize structures only present on HMW FVIII.


2002 ◽  
Author(s):  
Rudolf Zitny ◽  
Jiří Sestak ◽  
Alexander Tsiapouris ◽  
Lothar Linke

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 463-P
Author(s):  
TOMONORI KIMURA ◽  
YOSHITAKA HASHIMOTO ◽  
TAKAFUMI SENMARU ◽  
EMI USHIGOME ◽  
MASAHIDE HAMAGUCHI ◽  
...  
Keyword(s):  

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