scholarly journals Mechanisms for the inhibition of amyloid aggregation by small ligands

2016 ◽  
Vol 36 (5) ◽  
Author(s):  
Matteo Ramazzotti ◽  
Fabrizio Melani ◽  
Laura Marchi ◽  
Nadia Mulinacci ◽  
Stefano Gestri ◽  
...  

This work investigates by biochemical, biophysical and MD techniques the opposite anti-amyloid properties of resveratrol and rosmarinic acid on the aggregation of hen egg white lysozyme (HEWL). Differences in association energy and contact maps were found that explain the different behaviours.

RSC Advances ◽  
2017 ◽  
Vol 7 (18) ◽  
pp. 10973-10984 ◽  
Author(s):  
W. Gospodarczyk ◽  
M. Kozak

The formation of amyloid plaques is being intensively studied, as this process underlies severe human diseases, including Alzheimer's disease, and the exact mechanism of this specific aggregation has not been resolved yet.


1997 ◽  
Vol 94 ◽  
pp. 356-364 ◽  
Author(s):  
M Faraggi ◽  
E Bettelheim ◽  
M Weinstein

2021 ◽  
pp. 138830
Author(s):  
Baoliang Ma ◽  
Haohao Wang ◽  
Yujie Liu ◽  
Fang Wu ◽  
Xudong Zhu

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