The Mechanism of Action of the Calcium Pump from Rabbit Muscle Sarcoplasmic Reticulum

1977 ◽  
Vol 5 (5) ◽  
pp. 1270-1272
Author(s):  
D. W. YATES ◽  
V. C. DUANCE ◽  
A. R. TEBAR ◽  
P. BUCKBERRY
1974 ◽  
Vol 249 (10) ◽  
pp. 3166-3169 ◽  
Author(s):  
Olov Wålinder ◽  
Jayant G. Joshi

1985 ◽  
Vol 40 (7-8) ◽  
pp. 571-575 ◽  
Author(s):  
Wilhelm Hasselbach ◽  
Andrea Migala

Abstract The decline of the transport ratio of the sarcoplasmic calcium pump observed in a recent study (A. results from the retardation of calcium oxalate precipitation at low calcium/protein ratios. The prevailing high internal calcium level supports a rapid calcium backflux and a compensatory ATP hydrolysis during net calcium uptake which reduces the transport ratio. Yet, the determined calcium back­ flux does not fully account for the decline of the transport ratio. A supposed modulation of the stoichiometry of the pump by external calcium (0.1 μм) is at variance with results of previous studies showing a constant transport ratio of two in the same calcium concentration range.


Sign in / Sign up

Export Citation Format

Share Document