Contractile and non-contractile protein synthesis in the small and large intestine and their response to acute ethanol dosage

1994 ◽  
Vol 22 (2) ◽  
pp. 194S-194S ◽  
Author(s):  
JASPAUL S. MARWAY ◽  
TAHIR SIDDIQ ◽  
PAUL GIBBS ◽  
PAUL EDWARDS ◽  
VICTOR R. PREEDY
Keyword(s):  
Protein Synthesis ◽  
Large Intestine ◽  
Contractile Protein ◽  
Acute Ethanol ◽  
Ethanol Dosage ◽  
Small And Large Intestine

scholarly journals Contribution of rat liver and gastrointestinal tract to whole-body protein synthesis in the rat

1980 ◽  
Vol 186 (1) ◽  
pp. 381-383 ◽  
Author(s):  
M A McNurlan ◽  
P J Garlick
Keyword(s):  
Protein Synthesis ◽  
Gastrointestinal Tract ◽  
Rat Liver ◽  
Large Intestine ◽  
Whole Body ◽  
Body Protein ◽  
Small And Large Intestine

The rate of protein synthesis was assessed in liver, stomach, small and large intestine and in the whole body of rats by injection of 100 mumol of [14C]leucine/100 g body wt. In each of the tissues turnover was very rapid, so that taken together they accounted for 43% of the protein synthesized by the whole animal.

Cardiac contractile protein synthesis in hypertension: modulation by acute ethanol toxicity

1994 ◽  
Vol 22 (2) ◽  
pp. 170S-170S ◽  
Author(s):  
TAHIR SIDDIQ ◽  
PETER J. RICHARDSON ◽  
VICTOR R. PREEDY
Keyword(s):  
Protein Synthesis ◽  
Contractile Protein ◽  
Cardiac Contractile ◽  
Ethanol Toxicity ◽  
Acute Ethanol

scholarly journals Protein synthesis during the developmental growth of the small and large intestine of the rat

1984 ◽  
Vol 217 (2) ◽  
pp. 527-534 ◽  
Author(s):  
D F Goldspink ◽  
S E M Lewis ◽  
F J Kelly
Keyword(s):  
Protein Synthesis ◽  
Small Intestine ◽  
Large Intestine ◽  
Post Partum ◽  
Whole Body ◽  
Fractional Rate ◽  
Body Tissues ◽  
Developmental Growth ◽  
Small And Large Intestine

The developmental growth and associated changes in protein synthesis were measured (in vivo) in the combined small and large intestine from 18 days in utero to 105 weeks post partum. Similar post-natal (3-105 weeks) changes were also studied in the separated large and small intestine, and in the mucosal and muscularis externa + serosal layers of the small intestine. Although the protein and nucleic acid contents of the whole intestine increased throughout both pre- and post-natal life, the maximal (11%) intestinal contribution to whole-body growth occurred 3 weeks after birth; this value declined to only 2.5-3.5% at both extremes of the age range studied. Between the 18-day foetus and old age the fractional rate of protein synthesis decreased from 107 to 61% per day. This developmental decline (43%) was, however, much smaller than that found in most other body tissues over the same period. Similar developmental trends (between weaning and senility) were found in both the small and the large intestine when studied separately, the small intestine in all respects contributing proportionately more than the large intestine to both the combined intestinal and whole-body values. At each age the large intestine possessed significantly lower fractional rates of synthesis and associated ribosomal activities. For the most part, the fractional synthesis rates in the mucosa and serosa of the small intestine were very similar, with each declining slightly with increasing age. These developmental changes are discussed with respect to functional aspects within the gastrointestinal tract.

Comparison of Transport Capacity of Small and Large Intestine

1961 ◽  
Vol 41 (5) ◽  
pp. 500-504 ◽  
Author(s):  
N. Cordero ◽  
T. Hastings Wilson
Keyword(s):  
Large Intestine ◽  
Transport Capacity ◽  
Small And Large Intestine

scholarly journals Small and Large Intestine (II): Inflammatory Bowel Disease, Short Bowel Syndrome, and Malignant Tumors of the Digestive Tract

Nutrients ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 2325
Author(s):  
Yolanda Ber ◽  
Santiago García-Lopez ◽  
Carla J. Gargallo-Puyuelo ◽  
Fernando Gomollón
Keyword(s):  
Inflammatory Bowel Disease ◽  
Short Bowel Syndrome ◽  
Large Intestine ◽  
Malignant Tumors ◽  
Short Bowel ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Macro And Micronutrients ◽  
Enteral And Parenteral Nutrition ◽  
Small And Large Intestine

The small intestine is key in the digestion and absorption of macro and micronutrients. The large intestine is essential for the absorption of water, to allow adequate defecation, and to harbor intestinal microbiota, for which their nutritional role is as important as it is unknown. This article will describe the causes and consequences of malnutrition in patients with inflammatory bowel diseases, the importance of screening and replacement of micronutrient deficits, and the main indications for enteral and parenteral nutrition in these patients. We will also discuss the causes of short bowel syndrome, a complex entity due to anatomical or functional loss of part of the small bowel, which can cause insufficient absorption of liquid, electrolytes, and nutrients and lead to complex management. Finally, we will review the causes, consequences, and management of malnutrition in patients with malignant and benign digestive tumors, including neuroendocrine tumors (present not only in the intestine but also in the pancreas).

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