Vitamin D Receptor Genotypes in Chronic Renal Failure

2001 ◽  
Vol 101 (s45) ◽  
pp. 8P-8P
Author(s):  
E Mercer ◽  
KW Colston ◽  
JB Eastwood
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Vitamin D Receptor

Association between vitamin D receptor Fokl polymorphism and serum parathyroid hormone level in patients with chronic renal failure

2005 ◽  
Vol 28 (4) ◽  
pp. 117-121 ◽  
Author(s):  
E. Vigo Gago ◽  
C. Cadarso-Suárez ◽  
R. Perez-Fernandez ◽  
R. Romero Burgos ◽  
J. Devesa Mugica ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Parathyroid Hormone ◽  
Chronic Renal Failure ◽  
Vitamin D Receptor ◽  
Hormone Level ◽  
Parathyroid Hormone Level ◽  
Serum Parathyroid Hormone

Impaired homologous upregulation of vitamin D receptor in rats with chronic renal failure

1994 ◽  
Vol 266 (5) ◽  
pp. F706-F712 ◽  
Author(s):  
H. Koyama ◽  
Y. Nishizawa ◽  
M. Inaba ◽  
M. Hino ◽  
J. M. Prahl ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Vitamin D Receptor ◽  
Northern Blot Analysis ◽  
Dissociation Constants ◽  
Binding Capacity ◽  
Immunoblot Analysis ◽  
Dihydroxyvitamin D3 ◽  
Protein Levels

We studied the homologous regulation of the vitamin D receptor (VDR) in the duodenum of rats with chronic renal failure. Mean basal nuclear 3H-labeled 1 alpha,25-dihydroxyvitamin D3 ([3H]1,25(OH)2D3) binding capacity was 48 and 43 fmol/mg protein for sham-operated and uremic rats with similar dissociation constants (Kd), respectively. These results coincided with those of immunoblot analysis, which found that VDR protein level of uremic rats was 87.6% that of sham-operated rats. In uremic rats, 1,25(OH)2D3, 2.0 micrograms/kg, failed to upregulate VDR protein levels until 24 h, in contrast to the significant increases produced in sham-operated rats at both 12 (1.55-fold) and 24 h (1.75-fold). Baseline level of VDR mRNA in uremic rats, determined by Northern blot analysis, was comparable to that in sham-operated rats. Treatment with 1,25(OH)2D3 slightly decreased VDR mRNA at 6-24 h in the sham-operated rats, in contrast to the increase seen at 6 h in uremic rats. These results suggest that the homologous upregulation of VDR was attenuated in rats with chronic renal failure because of an impairment at a translational and/or posttranslational step.

scholarly journals PREVALENCE OF VITAMIN D DEFICIENCY IN DIFFERENT GROUPS OF CHRONIC RENAL FAILURE PATIENTS

2015 ◽  
Vol 21 (3) ◽  
pp. 887-890 ◽  
Author(s):  
Bistra T. Galunska ◽  
◽  
Daniela I. Gerova ◽  
Dobrin N. Paskalev ◽  
Rositza Y. Zorcheva ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Vitamin D Deficiency

Vitamin D and its analogs in chronic renal failure

1997 ◽  
Vol 7 (S3) ◽  
pp. 202-208 ◽  
Author(s):  
E. Slatopolsky ◽  
A. J. Brown
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Chronic Renal Failure

VITAMIN-D METABOLISM IN CHRONIC RENAL FAILURE

The Lancet ◽  
1975 ◽  
Vol 305 (7916) ◽  
pp. 1147
Author(s):  
C.E. Dent ◽  
Mercedes Domenech ◽  
J.M. Gertner
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Vitamin D Metabolism
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