Impact of transient hypotension on regional cerebral blood flow in humans

2015 ◽  
Vol 129 (2) ◽  
pp. 169-178 ◽  
Author(s):  
Nia C.S. Lewis ◽  
Kurt J. Smith ◽  
Anthony R. Bain ◽  
Kevin W. Wildfong ◽  
Tianne Numan ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Vertebral Artery ◽  
Regional Cerebral Blood Flow ◽  
Internal Carotid ◽  
Regional Cerebral Blood

Diameter reductions in the internal carotid artery (ICA) and vertebral artery (VA) contribute to the decline in brain blood with hypotension. The decline in vertebral blood flow with hypotension was greater when carbon dioxide was low; this was not apparent in the ICA.

Augmenting Regional Cerebral Blood Flow Using External-to-Internal Carotid Artery Flow Diversion Method

2009 ◽  
Vol 37 (12) ◽  
pp. 2428-2435 ◽  
Author(s):  
Afshin A. Divani ◽  
Tamara L. Berezina ◽  
Gabriela Vazquez ◽  
Sergey B. Zaets ◽  
Ramachandra Tummala ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Regional Cerebral Blood Flow ◽  
Internal Carotid ◽  
Flow Diversion ◽  
Regional Cerebral Blood ◽  
Artery Flow

scholarly journals Intraoperative Regional Cerebral Blood Flow During Carotid Endarterectomy

1981 ◽  
Vol 8 (3) ◽  
pp. 235-241 ◽  
Author(s):  
David W. Rowed ◽  
Miklos I. Vilaghy
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Neurological Deficit ◽  
Regional Cerebral Blood Flow ◽  
Internal Carotid ◽  
Regional Cerebral Blood ◽  
Stump Pressure ◽  
Probe Holder

SUMMARY:Regional cerebral blood flow (rCBF) during internal carotid artery (ICA) occlusion for endarterectomy can be measured without inconvenience using the probe holder illustrated.When mean ipsilateral hemispheric CBF exceeds 20 ml/100 gm/min, an intraluminal bypass is not necessary (63% of patients), except in patients with extensive cerebrovascular disease in whom rCBF should also exceed 20 ml/100 gm/min in all areas. ICA “stump” pressure is falsely high in about 20% of patients, and is therefore not a dependable criterion for selecting patients who need shunting.While intraoperative shunting is capable of restoring pre-occlusion CBF levels, it does not eliminate the risk of intraoperative ischemic neurological deficit of probable embolic origin.

Effect of Serotonin on Regional Cerebral Blood Flow (rCBF) in Man

Cephalalgia ◽  
1981 ◽  
Vol 1 (1) ◽  
pp. 7-10 ◽  
Author(s):  
Jes Olesen
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Cerebral Hemisphere ◽  
Regional Cerebral Blood Flow ◽  
Internal Carotid ◽  
Constant Infusion ◽  
Regional Cerebral Blood ◽  
The Difference

With the intraarterial 133Xenon injection method, regional cerebral blood flow (rCBF) was measured from 35 regions of a cerebral hemisphere. The effect of a constant infusion of serotonin (10–33 μg/min) for 2–5 min into the internal carotid artery was studied eight times in five patients. During rest, mean rCBF was 43.5 ml/100g/min as compared to 42.6 ml/100g/min during serotonin infusion. The latter value was altered to 42.8 ml/100g/min if correction for altered PaCO2 was carried out. In neither instance was the difference significant. It is concluded that circulating serotonin is unlikely to cause the cerebrovascular alterations associated with classical migraine attacks.

scholarly journals Retraction of the Internal Carotid Artery and Measurement of the Regional Cerebral Blood Flow in Basilar Top Aneurysmal Surgery

1991 ◽  
Vol 19 (3) ◽  
pp. 348-352
Author(s):  
Shuichi OKI ◽  
Toshinori NAKAHARA ◽  
Zainal MUTTAQIN ◽  
Yoshio TOKUDA ◽  
Katsuya EMOTO ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Regional Cerebral Blood Flow ◽  
Internal Carotid ◽  
Regional Cerebral Blood

scholarly journals Effect of healthy aging on cerebral blood flow, CO2 reactivity, and neurovascular coupling during exercise

2018 ◽  
Vol 125 (6) ◽  
pp. 1917-1930 ◽  
Author(s):  
Daniela Nowak-Flück ◽  
Philip N. Ainslie ◽  
Anthony R. Bain ◽  
Amar Ahmed ◽  
Kevin W. Wildfong ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Carotid Artery ◽  
Internal Carotid Artery ◽  
Healthy Aging ◽  
Internal Carotid ◽  
Neurovascular Coupling ◽  
Dynamic Exercise ◽  
Older Individuals

We sought to make the first comparisons of duplex Doppler ultrasonography-derived measures of cerebral blood flow during exercise in young and older individuals and to assess whether healthy aging influences the effect of exercise on neurovascular coupling (NVC) and cerebral vascular reactivity to changes in carbon dioxide (CVRco2). In 10 healthy young (23 ± 2 yr; mean ± SD) and 9 healthy older (66 ± 3 yr) individuals, internal carotid artery (ICA) and vertebral artery (VA) blood flows were concurrently measured, along with middle and posterior cerebral artery mean blood velocity (MCAvmean and PCAvmean). Measures were made at rest and during leg cycling (75 W and 35% maximum aerobic workload). ICA and VA blood flow during dynamic exercise, undertaken at matched absolute (ICA: young 336 ± 95, older 352 ± 155; VA: young 95 ± 43, older 100 ± 30 ml/min) and relative (ICA: young 355 ± 125, older 323 ± 153; VA: young 115 ± 48, older 110 ± 32 ml/min) intensities, were not different between groups ( P > 0.670). The PCAvmean responses to visual stimulation (NVC) were blunted in older versus younger group at rest (16 ± 6% vs. 23 ± 7%, P < 0.026) and exercise; however, these responses were not changed from rest to exercise in either group. The ICA and VA CVRco2 were comparable in both groups and unaltered during exercise. Collectively, our findings suggest that 1) ICA and VA blood flow responses to dynamic exercise are similar in healthy young and older individuals, 2) NVC is blunted in healthy older individuals at rest and exercise but is not different between rest to exercise in either group, and 3) CVRco2 is similar during exercise in healthy young and older groups. NEW & NOTEWORTHY Internal carotid artery and vertebral artery blood flow responses to dynamic exercise are similar in healthy young and older individuals. Neurovascular coupling and cerebrovascular carbon dioxide reactivity, two key mechanisms mediating the cerebral blood flow responses to exercise, are generally unaffected by exercise in both healthy young and older individuals.

Sign in / Sign up

Export Citation Format

Share Document